Automated quantitative multiplex immunofluorescence in situ imaging identifies phospho-S6 and phospho-PRAS40 as predictive protein biomarkers for prostate cancer lethality

BACKGROUND: We have witnessed significant progress in gene-based approaches to cancer prognostication, promising early intervention for high-risk patients and avoidance of overtreatment for low-risk patients. However, there has been less advancement in protein-based approaches, even though perturbed...

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Autori principali: Shipitsin, Michail, Small, Clayton, Giladi, Eldar, Siddiqui, Summar, Choudhury, Sibgat, Hussain, Sadiq, Huang, Yi E, Chang, Hua, Rimm, David L, Berman, David M, Nifong, Thomas P, Blume-Jensen, Peter
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2014
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4114438/
https://ncbi.nlm.nih.gov/pubmed/25075204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1477-5956-12-40
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