Identification of Direct Target Engagement Biomarkers for Kinase-Targeted Therapeutics

Por Paweletz, Cloud P., Andersen, Jannik N., Pollock, Roy, Nagashima, Kumiko, Hayashi, Mansuo L., Yu, Shangshuan U., Guo, Hongbo, Bobkova, Ekaterina V., Xu, Zangwei, Northrup, Alan, Blume-Jensen, Peter, Hendrickson, Ronald C., Chi, An
Publicado em 2011

A gene expression signature of RAS pathway dependence predicts response to PI3K and RAS pathway inhibitors and expands the population of RAS pathway activated tumors

Por Loboda, Andrey, Nebozhyn, Michael, Klinghoffer, Rich, Frazier, Jason, Chastain, Michael, Arthur, William, Roberts, Brian, Zhang, Theresa, Chenard, Melissa, Haines, Brian, Andersen, Jannik, Nagashima, Kumiko, Paweletz, Cloud, Lynch, Bethany, Feldman, Igor, Dai, Hongyue, Huang, Pearl, Watters, James
Publicado em 2010

Dissecting the tumor micro-environment in triple negative breast cancer identifies a mutually exclusive expression pattern of the immune co-inhibitory molecules B7-H4 and PD-L1

Por Shaffer, Donald R, Cortez-Retamozo, Virna, Nagashima, Kumiko, Zi, Tong, Shu, ChengYi J, Feldman, Igor, Neumeister, Veronique, Smith, Jeff, Zafari, Mohammad, Larson, Rebecca, Silver, Matthew, Mabry, Robert, Briskin, Michael, Novobrantseva, Tanya, Rimm, David, Sathyanarayanan, Sriram
Publicado no J Immunother Cancer (2015)

Sensitive multiplexed analysis of kinase activities and activity-based kinase identification

Por Kubota, Kazuishi, Anjum, Rana, Yu, Yonghao, Kunz, Ryan C, Andersen, Jannik N, Kraus, Manfred, Keilhack, Heike, Nagashima, Kumiko, Krauss, Stefan, Paweletz, Cloud, Hendrickson, Ronald C, Feldman, Adam S, Wu, Chin-Lee, Rush, John, Villén, Judit, Gygi, Steven P
Publicado em 2009

Genetic and Pharmacological Inhibition of PDK1 in Cancer Cells: CHARACTERIZATION OF A SELECTIVE ALLOSTERIC KINASE INHIBITOR

Por Nagashima, Kumiko, Shumway, Stuart D., Sathyanarayanan, Sriram, Chen, Albert H., Dolinski, Brian, Xu, Youyuan, Keilhack, Heike, Nguyen, Thi, Wiznerowicz, Maciej, Li, Lixia, Lutterbach, Bart A., Chi, An, Paweletz, Cloud, Allison, Timothy, Yan, Youwei, Munshi, Sanjeev K., Klippel, Anke, Kraus, Manfred, Bobkova, Ekaterina V., Deshmukh, Sujal, Xu, Zangwei, Mueller, Uwe, Szewczak, Alexander A., Pan, Bo-Sheng, Richon, Victoria, Pollock, Roy, Blume-Jensen, Peter, Northrup, Alan, Andersen, Jannik N.
Publicado em 2011