Sensitive multiplexed analysis of kinase activities and activity-based kinase identification

Constitutive activation of one or more kinase signaling pathways is a hallmark of many cancers. Here we extend the previously described mass spectrometry–based KAYAK approach by monitoring kinase activities from multiple signaling pathways simultaneously. This improved single-reaction strategy, whic...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Kubota, Kazuishi, Anjum, Rana, Yu, Yonghao, Kunz, Ryan C, Andersen, Jannik N, Kraus, Manfred, Keilhack, Heike, Nagashima, Kumiko, Krauss, Stefan, Paweletz, Cloud, Hendrickson, Ronald C, Feldman, Adam S, Wu, Chin-Lee, Rush, John, Villén, Judit, Gygi, Steven P
Formato: Artigo
Lenguaje:Inglês
Publicado: 2009
Materias:
Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3129615/
https://ncbi.nlm.nih.gov/pubmed/19801977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt.1566
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares