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Sensitive multiplexed analysis of kinase activities and activity-based kinase identification
Constitutive activation of one or more kinase signaling pathways is a hallmark of many cancers. Here we extend the previously described mass spectrometry–based KAYAK approach by monitoring kinase activities from multiple signaling pathways simultaneously. This improved single-reaction strategy, whic...
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| Main Authors: | , , , , , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2009
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3129615/ https://ncbi.nlm.nih.gov/pubmed/19801977 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt.1566 |
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