Situs inversus and embryonic ciliary morphogenesis defects in mouse mutants lacking the KIF3A subunit of kinesin-II

بواسطة Marszalek, Joseph R., Ruiz-Lozano, Pilar, Roberts, Elizabeth, Chien, Kenneth R., Goldstein, Lawrence S. B.
منشور في 1999

Novel Dendritic Kinesin Sorting Identified by Different Process Targeting of Two Related Kinesins: KIF21A and KIF21B

بواسطة Marszalek, Joseph R., Weiner, Joshua A., Farlow, Samuel J., Chun, Jerold, Goldstein, Lawrence S.B.
منشور في 1999

Cork-in-bottle mechanism of inhibitor binding to mammalian complex I

بواسطة Chung, Injae, Serreli, Riccardo, Cross, Jason B., Di Francesco, M. Emilia, Marszalek, Joseph R., Hirst, Judy
الحاوية / القاعدة Sci Adv (2021)

Biological and metabolic effects of IACS-010759, an OxPhos inhibitor, on chronic lymphocytic leukemia cells

بواسطة Vangapandu, Hima V., Alston, Brandon, Morse, Joshua, Ayres, Mary L., Wierda, William G., Keating, Michael J., Marszalek, Joseph R., Gandhi, Varsha
الحاوية / القاعدة Oncotarget (2018)

Pharmacodynamics and Proteomic Analysis of Acalabrutinib Therapy: Similarity of On-Target Effects to Ibrutinib and Rationale for Combination Therapy

بواسطة Patel, Viral Kumar, Lamothe, Betty, Ayres, Mary L., Gay, Jason, Cheung, Jean, Balakrishnan, Kumudha, Ivan, Cristina, Morse, Joshua, Nelson, Mark, Keating, Michael J., Wierda, William G., Marszalek, Joseph R., Gandhi, Varsha
الحاوية / القاعدة Leukemia (2017)

Elevated Endogenous SDHA Drives Pathological Metabolism in Highly Metastatic Uveal Melanoma

بواسطة Chattopadhyay, Chandrani, Oba, Junna, Roszik, Jason, Marszalek, Joseph R., Chen, Ken, Qi, Yuan, Eterovic, Karina, Robertson, A. Gordon, Burks, Jared K., McCannel, Tara A., Grimm, Elizabeth A., Woodman, Scott E.
الحاوية / القاعدة Invest Ophthalmol Vis Sci (2019)

Niraparib activates interferon signaling and potentiates anti-PD-1 antibody efficacy in tumor models

بواسطة Wang, Zebin, Sun, Kaiming, Xiao, Yonghong, Feng, Bin, Mikule, Keith, Ma, XiaoYan, Feng, Ningping, Vellano, Christopher P., Federico, Lorenzo, Marszalek, Joseph R., Mills, Gordon B., Hanke, Jeffrey, Ramaswamy, Sridhar, Wang, Jing
الحاوية / القاعدة Sci Rep (2019)

Inhibition of Oxidative Phosphorylation Reverses Bone Marrow Hypoxia Visualized in Imageable Syngeneic B-ALL Mouse Model

بواسطة Rytelewski, Mateusz, Harutyunyan, Karine, Baran, Natalia, Mallampati, Saradhi, Zal, M. Anna, Cavazos, Antonio, Butler, Jason M., Konoplev, Sergej, El Khatib, Mirna, Plunkett, Shane, Marszalek, Joseph R., Andreeff, Michael, Zal, Tomasz, Konopleva, Marina
الحاوية / القاعدة Front Oncol (2020)

Antileukemia activity of the novel peptidic CXCR4 antagonist LY2510924 as monotherapy and in combination with chemotherapy

بواسطة Cho, Byung-Sik, Zeng, Zhihong, Mu, Hong, Wang, Zhiqiang, McQueen, Teresa, Protopopova, Marina, Cortes, Jorge, Marszalek, Joseph R., Peng, Sheng-Bin, Ma, Wencai, Davis, R. Eric, Thornton, Donald E., Andreeff, Michael, Konopleva, Marina
الحاوية / القاعدة Blood (2015)

Mitochondrial Complex I Inhibitors Expose a Vulnerability for Selective Killing of Pten-Null Cells

بواسطة Naguib, Adam, Mathew, Grinu, Reczek, Colleen R., Watrud, Kaitlin, Ambrico, Alexandra, Herzka, Tali, Salas, Irene Casanova, Lee, Matthew F., El-Amine, Nour, Zheng, Wu, Di Francesco, M. Emilia, Marszalek, Joseph R., Pappin, Darryl J., Chandel, Navdeep S., Trotman, Lloyd C.
الحاوية / القاعدة Cell Rep (2018)

Generation and testing of clinical-grade exosomes for pancreatic cancer

بواسطة Mendt, Mayela, Kamerkar, Sushrut, Sugimoto, Hikaru, McAndrews, Kathleen M., Wu, Chia-Chin, Gagea, Mihai, Yang, Sujuan, Blanko, Elena V. Rodriges, Peng, Qian, Ma, Xiaoyan, Marszalek, Joseph R., Maitra, Anirban, Yee, Cassian, Rezvani, Katayoun, Shpall, Elizabeth, LeBleu, Valerie S., Kalluri, Raghu
الحاوية / القاعدة JCI Insight (2018)

Mechanism-Specific Pharmacodynamics of a Novel Complex-I Inhibitor Quantified by Imaging Reversal of Consumptive Hypoxia with [(18)F]FAZA PET In Vivo

بواسطة Gammon, Seth T., Pisaneschi, Federica, Bandi, Madhavi L., Smith, Melinda G., Sun, Yuting, Rao, Yi, Muller, Florian, Wong, Franklin, De Groot, John, Ackroyd, Jeffrey, Mawlawi, Osama, Davies, Michael A., Vashisht Gopal, Y.N., Di Francesco, M. Emilia, Marszalek, Joseph R., Dewhirst, Mark, Piwnica-Worms, David
الحاوية / القاعدة Cells (2019)

PPM1D Mutations Drive Clonal Hematopoiesis in Response to Cytotoxic Chemotherapy

بواسطة Hsu, Joanne I., Dayaram, Tajhal, Tovy, Ayala, De Braekeleer, Etienne, Jeong, Mira, Wang, Feng, Zhang, Jianhua, Heffernan, Timothy P., Gera, Sonal, Kovacs, Jeffrey J., Marszalek, Joseph R., Bristow, Christopher, Yan, Yuanqing, Garcia-Manero, Guillermo, Kantarjian, Hagop, Vassiliou, George, Futreal, P. Andrew, Donehower, Lawrence A., Takahashi, Koichi, Goodell, Margaret A.
الحاوية / القاعدة Cell Stem Cell (2018)

Development of novel cellular histone-binding and chromatin-displacement assays for bromodomain drug discovery

بواسطة Zhan, Yanai, Kost-Alimova, Maria, Shi, Xi, Leo, Elisabetta, Bardenhagen, Jennifer P., Shepard, Hannah E., Appikonda, Srikanth, Vangamudi, Bhavatarini, Zhao, Shuping, Tieu, Trang N., Jiang, Shiming, Heffernan, Timothy P., Marszalek, Joseph R., Toniatti, Carlo, Draetta, Giulio, Tyler, Jessica, Barton, Michelle, Jones, Philip, Palmer, Wylie S., Geck Do, Mary K., Andersen, Jannik N.
الحاوية / القاعدة Epigenetics Chromatin (2015)

Hypoxia-activated prodrug TH-302 targets hypoxic bone marrow niches in pre-clinical leukemia models

بواسطة Benito, Juliana, Ramirez, Marc, Millward, Niki Zacharias, Velez, Juliana, Harutyunyan, Karine, Lu, Hongbo, Shi, Yuexi, Matre, Polina, Jacamo, Rodrigo, Ma, Helen, Konoplev, Sergej, McQueen, Teresa, Volgin, Andrei, Protopopova, Marina, Mu, Hong, Lee, Jaehyuk, Bhattacharya, Pratip, Marszalek, Joseph R, Davis, R. Eric, Bankson, Jim, Cortes, Jorge, Hart, Charles P, Andreeff, Michael, Konopleva, Marina
الحاوية / القاعدة Clin Cancer Res (2015)

The SMARCA2/4 ATPase domain surpasses the bromodomain as a drug target in SWI/SNF mutant cancers: Insights from cDNA rescue and PFI-3 inhibitor studies

بواسطة Vangamudi, Bhavatarini, Paul, Thomas A., Shah, Parantu K., Kost-Alimova, Maria, Nottebaum, Lisa, Shi, Xi, Zhan, Yanai, Leo, Elisabetta, Mahadeshwar, Harshad S., Protopopov, Alexei, Futreal, Andrew, Tieu, Trang N., Peoples, Mike, Heffernan, Timothy P., Marszalek, Joseph R., Toniatti, Carlo, Petrocchi, Alessia, Verhelle, Dominique, Owen, Dafydd R., Draetta, Giulio, Jones, Philip, Palmer, Wylie S., Sharma, Shikhar, Andersen, Jannik N.
الحاوية / القاعدة Cancer Res (2015)

Pharmacologic profiling of patient-derived xenograft models of primary treatment-naïve triple-negative breast cancer

بواسطة Powell, Reid T., Redwood, Abena, Liu, Xuan, Guo, Lei, Cai, Shirong, Zhou, Xinhui, Tu, Yizheng, Zhang, Xiaomei, Qi, Yuan, Jiang, Yan, Echeverria, Gloria, Feng, Ningping, Ma, XiaoYan, Giuliani, Virginia, Marszalek, Joseph R., Heffernan, Timothy P., Vellano, Christopher P., White, Jason B., Stephan, Clifford, Davies, Peter J., Moulder, Stacy, Symmans, W. Fraser, Chang, Jeffrey T., Piwnica-Worms, Helen
الحاوية / القاعدة Sci Rep (2020)

Mutations in the SWI/SNF complex induce a targetable dependence on oxidative phosphorylation in lung cancer

بواسطة Deribe, Yonathan Lissanu, Sun, Yuting, Terranova, Christopher, Khan, Fatima, Martinez-Ledesma, Juan, Gay, Jason, Gao, Guang, Mullinax, Robert A., Khor, Tin, Feng, Ningping, Lin, Yu-Hsi, Wu, Chia-Chin, Reyes, Claudia, Peng, Qian, Robinson, Frederick, Inoue, Akira, Kochat, Veena, Liu, Chang-Gong, Asara, John M., Moran, Cesar, Muller, Florian, Wang, Jing, Fang, Bingliang, Papadimitrakopoulou, Vassiliki, Wistuba, Ignacio I., Rai, Kunal, Marszalek, Joseph R., Futreal, P. Andrew
الحاوية / القاعدة Nat Med (2018)

Resistance to neoadjuvant chemotherapy in triple negative breast cancer mediated by a reversible drug-tolerant state

بواسطة Echeverria, Gloria V., Ge, Zhongqi, Seth, Sahil, Zhang, Xiaomei, Jeter-Jones, Sabrina, Zhou, Xinhui, Cai, Shirong, Tu, Yizheng, McCoy, Aaron, Peoples, Michael, Sun, Yuting, Qiu, Huan, Chang, Qing, Bristow, Christopher, Carugo, Alessandro, Shao, Jiansu, Ma, Xiaoyan, Harris, Angela, Mundi, Prabhjot, Lau, Rosanna, Ramamoorthy, Vandhana, Wu, Yun, Alvarez, Mariano J., Califano, Andrea, Moulder, Stacy L., Symmans, William F., Marszalek, Joseph R., Heffernan, Timothy P., Chang, Jeffrey T., Piwnica-Worms, Helen
الحاوية / القاعدة Sci Transl Med (2019)

An Enolase Inhibitor for the Targeted Treatment of ENO1-Deleted Cancers

بواسطة Lin, Yu-Hsi, Satani, Nikunj, Hammoudi, Naima, Yan, Victoria C., Barekatain, Yasaman, Khadka, Sunada, Ackroyd, Jeffrey J., Georgiou, Dimitra K., Pham, Cong-Dat, Arthur, Kenisha, Maxwell, David, Peng, Zhenghong, Leonard, Paul G., Czako, Barbara, Pisaneschi, Federica, Mandal, Pijus, Sun, Yuting, Zielinski, Rafal, Pando, Susana Castro, Wang, Xiaobo, Tran, Theresa, Xu, Quanyu, Wu, Qi, Jiang, Yongying, Kang, Zhijun, Asara, John M., Priebe, Waldemar, Bornmann, William, Marszalek, Joseph R., DePinho, Ronald A., Muller, Florian L.
الحاوية / القاعدة Nat Metab (2020)