Mdm2 inhibitor Nutlin-3a induces p53-mediated apoptosis by transcription-dependent and transcription-independent mechanisms and may overcome Atm-mediated resistance to fludarabine...

od Kojima, Kensuke, Konopleva, Marina, McQueen, Teresa, O'Brien, Susan, Plunkett, William, Andreeff, Michael
Izdano 2006

p53 activation of mesenchymal stromal cells partially abrogates microenvironment-mediated resistance to FLT3 inhibition in AML through HIF-1α–mediated down-regulation of CXCL12

od Kojima, Kensuke, McQueen, Teresa, Chen, Ye, Jacamo, Rodrigo, Konopleva, Marina, Shinojima, Naoki, Shpall, Elizabeth, Huang, Xuelin, Andreeff, Michael
Izdano 2011

HDAC inhibition by SNDX-275 (Entinostat) restores expression of silenced leukemia-associated transcription factors Nur77 and Nor1 and of key pro-apoptotic proteins in AML

od Zhou, Liran, Ruvolo, Vivian R., McQueen, Teresa, Chen, Wenjing, Samudio, Ismael J., Conneely, Orla, Konopleva, Marina, Andreeff, Michael
Izdano 2012

Triptolide induces caspase-dependent cell death mediated via the mitochondrial pathway in leukemic cells

od Carter, Bing Z., Mak, Duncan H., Schober, Wendy D., McQueen, Teresa, Harris, David, Estrov, Zeev, Evans, Randall L., Andreeff, Michael
Izdano 2006

Regulation of survivin expression through Bcr-Abl/MAPK cascade: targeting survivin overcomes imatinib resistance and increases imatinib sensitivity in imatinib-responsive CML cells

od Carter, Bing Z., Mak, Duncan H., Schober, Wendy D., Cabreira-Hansen, Maria, Beran, Miloslav, McQueen, Teresa, Chen, Wenjing, Andreeff, Michael
Izdano 2006

MDM2 antagonists induce p53-dependent apoptosis in AML: implications for leukemia therapy

od Kojima, Kensuke, Konopleva, Marina, Samudio, Ismael J., Shikami, Masato, Cabreira-Hansen, Maria, McQueen, Teresa, Ruvolo, Vivian, Tsao, Twee, Zeng, Zhihong, Vassilev, Lyubomir T., Andreeff, Michael
Izdano 2005

Blockade of MEK and MDM2 synergistically induces apoptosis in acute myeloid leukemia via BH3-only proteins Puma and Bim

od Zhang, Weiguo, Konopleva, Marina, Burks, Jared K., Dywer, Karen C., Schober, Wendy D., Yang, Jer-Yen, McQueen, Teresa J., Hung, Mien-Chie, Andreeff, Michael
Izdano 2010

Triterpenoids Display Single Agent Anti-tumor Activity in a Transgenic Mouse Model of Chronic Lymphocytic Leukemia and Small B Cell Lymphoma

od Kress, Christina L., Konopleva, Marina, Martínez-García, Vanesa, Krajewska, Maryla, Lefebvre, Sophie, Hyer, Marc L., McQueen, Teresa, Andreeff, Michael, Reed, John C., Zapata, Juan M.
Izdano 2007

PI3K inhibitor GDC-0941 enhances apoptotic effects of BH-3 mimetic ABT-737 in AML cells in the hypoxic bone marrow microenvironment

od Jin, Linhua, Tabe, Yoko, Kojima, Kensuke, Shikami, Masato, Benito, Julina, Ruvolo, Vivian, Wang, Rui-Yu, McQueen, Teresa, Ciurea, Stefan O., Miida, Takashi, Andreeff, Michael, Konopleva, Marina
Izdano 2013

Atg7 suppression enhances chemotherapeutic agent sensitivity and overcomes stroma-mediated chemoresistance in acute myeloid leukemia

od Piya, Sujan, Kornblau, Steven M., Ruvolo, Vivian R., Mu, Hong, Ruvolo, Peter P., McQueen, Teresa, Davis, R. Eric, Hail, Numsen, Kantarjian, Hagop, Andreeff, Michael, Borthakur, Gautam
Izdano u Blood (2016)

Synergistic effects of p53 activation via MDM2 inhibition in combination with inhibition of Bcl-2 or Bcr-Abl in CD34(+) proliferating and quiescent chronic myeloid leukemia blast c...

od Carter, Bing Z., Mak, Po Yee, Mak, Duncan H., Ruvolo, Vivian R., Schober, Wendy, McQueen, Teresa, Cortes, Jorge, Kantarjian, Hagop M., Champlin, Richard E., Konopleva, Marina, Andreeff, Michael
Izdano u Oncotarget (2015)

Mitochondrial Profiling of Acute Myeloid Leukemia in the Assessment of Response to Apoptosis Modulating Drugs

od Ishizawa, Jo, Kojima, Kensuke, McQueen, Teresa, Ruvolo, Vivian, Chachad, Dhruv, Nogueras-Gonzalez, Graciela M., Huang, Xuelin, Pierceall, William E., Dettman, E. J., Cardone, Michael H., Shacham, Sharon, Konopleva, Marina, Andreeff, Michael
Izdano u PLoS One (2015)

Antileukemia activity of the novel peptidic CXCR4 antagonist LY2510924 as monotherapy and in combination with chemotherapy

od Cho, Byung-Sik, Zeng, Zhihong, Mu, Hong, Wang, Zhiqiang, McQueen, Teresa, Protopopova, Marina, Cortes, Jorge, Marszalek, Joseph R., Peng, Sheng-Bin, Ma, Wencai, Davis, R. Eric, Thornton, Donald E., Andreeff, Michael, Konopleva, Marina
Izdano u Blood (2015)

Synergistic Targeting of AML Stem/Progenitor Cells With IAP Antagonist Birinapant and Demethylating Agents

od Carter, Bing Z., Mak, Po Yee, Mak, Duncan H., Shi, Yuexi, Qiu, Yihua, Bogenberger, James M., Mu, Hong, Tibes, Raoul, Yao, Hui, Coombes, Kevin R., Jacamo, Rodrigo O., McQueen, Teresa, Kornblau, Steven M., Andreeff, Michael
Izdano 2014

Tumor Trp53 status and genotype affect the bone marrow microenvironment in acute myeloid leukemia

od Jacamo, Rodrigo, Davis, R. Eric, Ling, Xiaoyang, Sonnylal, Sonali, Wang, Zhiqiang, Ma, Wencai, Zhang, Min, Ruvolo, Peter, Ruvolo, Vivian, Wang, Rui-Yu, McQueen, Teresa, Lowe, Scott, Zuber, Johannes, Kornblau, Steven M., Konopleva, Marina, Andreeff, Michael
Izdano u Oncotarget (2017)

BETP degradation simultaneously targets acute myelogenous leukemic stem cells and the microenvironment

od Piya, Sujan, Mu, Hong, Bhattacharya, Seemana, Lorenzi, Philip L., Davis, R. Eric, McQueen, Teresa, Ruvolo, Vivian, Baran, Natalia, Wang, Zhiqiang, Qian, Yimin, Crews, Craig M., Konopleva, Marina, Ishizawa, Jo, You, M. James, Kantarjian, Hagop, Andreeff, Michael, Borthakur, Gautam
Izdano u J Clin Invest (2019)

Role of MSC-derived Galectin 3 in the AML Microenvironment

od Ruvolo, Peter P., Ruvolo, Vivian R., Burks, Jared K., Qiu, YiHua, Wang, Rui-Yu, Shpall, Elizabeth J., Mirandola, Leonardo, Hail, Numsen, Zeng, Zhihong, McQueen, Teresa, Daver, Naval, Post, Sean M., Chiriva-Internati, Maurizio, Kornblau, Steven M., Andreeff, Michael
Izdano u Biochim Biophys Acta (2018)

Disruption of Wnt/β-catenin exerts anti-leukemia activity and synergizes with FLT3 inhibition in FLT3-mutant acute myeloid leukemia

od Jiang, Xuejie, Mak, Po Yee, Mu, Hong, Tao, Wenjing, Mak, Duncan H, Kornblau, Steven, Zhang, Qi, Ruvolo, Peter, Burks, Jared K, Zhang, Weiguo, McQueen, Teresa, Pan, Rongqing, Zhou, Hongsheng, Konopleva, Marina, Cortes, Jorge, Liu, Qifa, Andreeff, Michael, Carter, Bing Z
Izdano u Clin Cancer Res (2018)

Regulation of HIF-1α signaling and chemoresistance in acute lymphocytic leukemia under hypoxic conditions of the bone marrow microenvironment

od Frolova, Olga, Samudio, Ismael, Benito, Juliana Maria, Jacamo, Rodrigo, Kornblau, Steven M., Markovic, Ana, Schober, Wendy, Lu, Hongbo, Qiu, Yi Hua, Buglio, Daniela, McQueen, Teresa, Pierce, Sherry, Shpall, Elizabeth, Konoplev, Sergej, Thomas, Deborah, Kantarjian, Hagop, Lock, Richard, Andreeff, Michael, Konopleva, Marina
Izdano 2012

Single-cell mass cytometry reveals intracellular survival/proliferative signaling in FLT3-ITD-mutated AML stem/progenitor cells

od Han, Lina, Qiu, Peng, Zeng, Zhihong, Jorgensen, Jeffrey L, Mak, Duncan H, Burks, Jared K, Schober, Wendy, McQueen, Teresa J, Cortes, Jorge, Tanner, Scott D, Roboz, Gail J, Kantarjian, Hagop M, Kantarjian, Hagop M, Kornblau, Steven M, Guzman, Monica L, Andreeff, Michael, Konopleva, Marina
Izdano u Cytometry A (2015)