Mitochondrial Profiling of Acute Myeloid Leukemia in the Assessment of Response to Apoptosis Modulating Drugs

BH3 profiling measures the propensity of transformed cells to undergo intrinsic apoptosis and is determined by exposing cells to BH3-mimicking peptides. We hypothesized that basal levels of prosurvival BCL-2 family proteins may modulate the predictive power of BH3 profiling and termed it mitochondri...

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Detalhes bibliográficos
Publicado no:PLoS One
Principais autores: Ishizawa, Jo, Kojima, Kensuke, McQueen, Teresa, Ruvolo, Vivian, Chachad, Dhruv, Nogueras-Gonzalez, Graciela M., Huang, Xuelin, Pierceall, William E., Dettman, E. J., Cardone, Michael H., Shacham, Sharon, Konopleva, Marina, Andreeff, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4573975/
https://ncbi.nlm.nih.gov/pubmed/26375587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0138377
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