IMMU-17. REDUCING THE EX VIVO MANUFACTURING TIME OF EGFRVIII-SPECIFIC CHIMERIC ANTIGEN RECEPTOR (CAR) T CELLS IMPROVES PHENOTYPE AND DEMONSTRATES POTENT ANTI-GLIOMA FUNCTION IN VIV...

Por Tanaka, Ryuma, Caruso, Hillary, Ling, Xiaoyang, Najjar, Amer, Heimberger, Amy
Publicado no Neuro Oncol (2017)

IMMU-36. IMMUNE RESPONSES IN CANINE GLIOMAS ARE ENRICHED AT THE INFILTRATING EDGE OF ASTROCYTOMAS

Por Kassab, Cynthia, Levine, Jonathan, Boudreau, Beth, Ling, Xiaoyang, Burks, Jared K, Zhou, Shouhao, Verhaak, Roel, Heimberger, Amy
Publicado no Neuro Oncol (2018)

The CXCR4 Antagonist AMD3465 Regulates Oncogenic Signaling and Invasiveness In Vitro and Prevents Breast Cancer Growth and Metastasis In Vivo

Por Ling, Xiaoyang, Spaeth, Erika, Chen, Ye, Shi, Yuexi, Zhang, Weiguo, Schober, Wendy, Hail, Numsen, Konopleva, Marina, Andreeff, Michael
Publicado em 2013

MRx102, a triptolide derivative, has potent antileukemic activity in vitro and in a murine model of AML

Por Carter, Bing Z., Mak, Duncan H., Shi, Yuxie, Fidler, John M., Chen, Rong, Ling, Xiaoyang, Plunkett, William, Andreeff, Michael
Publicado em 2011

SCIDOT-23. LOW INTENSITY PULSED ULTRASOUND ENHANCES BLOOD-BRAIN BARRIER OPENING AND IMPROVES RESPONSE TO IMMUNOTHERAPY FOR GLIOBLASTOMA

Por Sabbagh, Aria, Marisetty, Anantha, Ott, Martina, Ling, Xiaoyang, Barton, Emily, Caruso, Hillary, Kong, Ling-Yuan, Rao, Ganesh, Canney, Michael, Heimberger, Amy B
Publicado no Neuro Oncol (2019)

IMPS-34 INNATE IMMUNOLOGICAL COMPENSATORY CONTROL OF GLIOMAGENESIS AND MALIGNANT TRANSFORMATION IN MURINE CD8α KNOCKOUT MODELS

Por Rao, Ganesh, Ling, Xiaoyang, Doucette, Tiffany, Yang, Yuhui, Kong, Ling-Yuan, Wei, Jun, Fuller, Gregory, Nwajei, Felix, Zhou, Shouhao, Caruso, Hillary, Vile, Richard, Heimberger, Amy
Publicado no Neuro Oncol (2015)

Mesenchymal Stem Cells Overexpressing IFN-β Inhibit Breast Cancer Growth and Metastases through Stat3 Signaling in a Syngeneic Tumor Model

Por Ling, Xiaoyang, Marini, Frank, Konopleva, Marina, Schober, Wendy, Shi, Yuexi, Burks, Jared, Clise-Dwyer, Karen, Wang, Rui-Yu, Zhang, Weiguo, Yuan, Xiaoqing, Lu, Hongbo, Caldwell, Lisa, Andreeff, Michael
Publicado em 2010

Targeting the leukemia microenvironment by CXCR4 inhibition overcomes resistance to kinase inhibitors and chemotherapy in AML

Por Zeng, Zhihong, Xi Shi, Yue, Samudio, Ismael J., Wang, Rui-Yu, Ling, Xiaoyang, Frolova, Olga, Levis, Mark, Rubin, Joshua B., Negrin, Robert R., Estey, Elihu H., Konoplev, Sergej, Andreeff, Michael, Konopleva, Marina
Publicado em 2009

Tumor Trp53 status and genotype affect the bone marrow microenvironment in acute myeloid leukemia

Por Jacamo, Rodrigo, Davis, R. Eric, Ling, Xiaoyang, Sonnylal, Sonali, Wang, Zhiqiang, Ma, Wencai, Zhang, Min, Ruvolo, Peter, Ruvolo, Vivian, Wang, Rui-Yu, McQueen, Teresa, Lowe, Scott, Zuber, Johannes, Kornblau, Steven M., Konopleva, Marina, Andreeff, Michael
Publicado no Oncotarget (2017)

IMPS-41 IMMUNE MODULATORY NANOPARTICLE THERAPEUTICS

Por Yaghi, Nasser, Wei, Jun, Hashimoto, Yuuri, Kong, Ling-Yuan, Gabrusiewicz, Konrad, Nduom, Edjah, Ling, Xiaoyang, Huang, Neal, Zhou, Shouhao, Levine, Jonathan, Fajt, Virginia, Levine, Gwendolyn, Porter, Brian, Tachikawa, Kiyoshi, Chivukula, Padmanabh, Webb, David, Payne, Joseph, Heimberger, Amy
Publicado no Neuro Oncol (2015)

Role of peroxisome proliferator-activated receptor-γ and its co-activator DRIP205 in cellular responses to CDDO (RTA-401) in AML

Por Tsao, Twee, Kornblau, Steven, Safe, Stephen, Watt, Julie C., Ruvolo, Vivian, Chen, Wenjing, Qiu, Yihua, Coombes, Kevin R., Ju, Zhenlin, Abdelrahim, Maen, Schober, Wendy, Ling, Xiaoyang, Kardassis, Dimitris, Meyer, Colin, Schimmer, Aaron, Kantarjian, Hagop, Andreeff, Michael, Konopleva, Marina
Publicado em 2010

MiR-138 exerts anti-glioma efficacy by targeting immune checkpoints

Por Wei, Jun, Nduom, Edjah K., Kong, Ling-Yuan, Hashimoto, Yuuri, Xu, Shuo, Gabrusiewicz, Konrad, Ling, Xiaoyang, Huang, Neal, Qiao, Wei, Zhou, Shouhao, Ivan, Cristina, Fuller, Greg N., Gilbert, Mark R., Overwijk, Willem, Calin, George A., Heimberger, Amy B.
Publicado no Neuro Oncol (2016)

IMPS-28 PD-L1 EXPRESSION AND PROGNOSTIC IMPACT IN GLIOBLASTOMA

Por Nduom, Edjah K., Wei, Jun, Yaghi, Nasser, Huang, Neal, Kong, Ling-Yuan, Gabrusiewicz, Konrad, Ling, Xiaoyang, Zhou, Shouhao, Ivan, Cristina, Chen, Jie Qing, Burks, Jared, Fuller, Greg, Calin, George, Conrad, Charles, Creasy, Caitlin, Ritthipichai, Krit, Radvanyi, Laszlo, Heimberger, Amy
Publicado no Neuro Oncol (2015)

Anti-PD-1 induces M1 polarization in the glioma microenvironment and exerts therapeutic efficacy in the absence of CD8 cytotoxic T cells

Por Rao, Ganesh, Latha, Khatri, Ott, Martina, Sabbagh, Aria, Marisetty, Anantha, Ling, Xiaoyang, Zamler, Daniel, Doucette, Tiffany A., Yang, Yuhui, Kong, Ling-Yuan, Wei, Jun, Fuller, Gregory N., Benavides, Fernando, Sonabend, Adam M., Long, James, Li, Shulin, Curran, Michael, Heimberger, Amy B.
Publicado no Clin Cancer Res (2020)

GENE-57. COMPARATIVE MOLECULAR LIFE HISTORY OF SPONTANEOUS CANINE AND HUMAN GLIOMA

Por Amin, Samirkumar, Anderson, Kevin, Bourdreau, Beth, Martínez, Emmanuel, Kocakavuk, Emre, Johnson, Kevin C, Barthel, Floris, Varn, Frederick, Kassab, Cynthia, Ling, Xiaoyang, Kim, Hoon, Barther, Mary, Yee Ngan, Chew, Dickinson, Peter, Packer, Rebecca, Taylor, Amanda, Rossmeisl, John, Heimberger, Amy, Levine, Jonathan, Verhaak, Roel
Publicado no Neuro Oncol (2019)

IT-22 TARGETING THE IMMUNE CHECKPOINT NETWORK WITH miR-138 EXERTS THERAPEUTIC EFFICACY IN MURINE MODELS OF GLIOMA

Por Nduom, Edjah K., Wei, Jun, Kong, Ling-Yuan, Xu, Shuo, Gabrusiewicz, Konrad, Ling, Xiaoyang, Huang, Neal, Qiao, Wei, Zhou, Shouhao, Ivan, Cristina, Chen, Jie Qing, Ji, Yongjie, Radvanyi, Laszlo, Fuller, Greg N., Gilbert, Mark, Conrad, Charles A., Overwijk, Willem, Calin, George A., Heimberger, Amy B.
Publicado em 2014

PD-L1 expression and prognostic impact in glioblastoma

Por Nduom, Edjah K., Wei, Jun, Yaghi, Nasser K., Huang, Neal, Kong, Ling-Yuan, Gabrusiewicz, Konrad, Ling, Xiaoyang, Zhou, Shouhao, Ivan, Cristina, Chen, Jie Qing, Burks, Jared K., Fuller, Greg N., Calin, George A., Conrad, Charles A., Creasy, Caitlin, Ritthipichai, Krit, Radvanyi, Laszlo, Heimberger, Amy B.
Publicado no Neuro Oncol (2016)

Osteopontin mediates glioblastoma-associated macrophage infiltration and is a potential therapeutic target

Por Wei, Jun, Marisetty, Anantha, Schrand, Brett, Gabrusiewicz, Konrad, Hashimoto, Yuuri, Ott, Martina, Grami, Zacharia, Kong, Ling-Yuan, Ling, Xiaoyang, Caruso, Hillary, Zhou, Shouhao, Wang, Y. Alan, Fuller, Gregory N., Huse, Jason, Gilboa, Eli, Kang, Nannan, Huang, Xingxu, Verhaak, Roel, Li, Shulin, Heimberger, Amy B.
Publicado no J Clin Invest (2018)

Immune modulatory nanoparticle therapeutics for intracerebral glioma

Por Yaghi, Nasser K., Wei, Jun, Hashimoto, Yuuri, Kong, Ling-Yuan, Gabrusiewicz, Konrad, Nduom, Edjah K., Ling, Xiaoyang, Huang, Neal, Zhou, Shouhao, Kerrigan, Brittany C. Parker, Levine, Jonathan M., Fajt, Virginia R., Levine, Gwendolyn, Porter, Brian F., Marcusson, Eric G., Tachikawa, Kiyoshi, Chivukula, Padmanabh, Webb, David C., Payne, Joseph E., Heimberger, Amy B.
Publicado no Neuro Oncol (2017)

AML-induced osteogenic differentiation in mesenchymal stromal cells supports leukemia growth

Por Battula, V. Lokesh, Le, Phuong M., Sun, Jeffrey C., Nguyen, Khoa, Yuan, Bin, Zhou, Ximin, Sonnylal, Sonali, McQueen, Teresa, Ruvolo, Vivian, Michel, Keith A., Ling, Xiaoyang, Jacamo, Rodrigo, Shpall, Elizabeth, Wang, Zhiqiang, Rao, Arvind, Al-Atrash, Gheath, Konopleva, Marina, Davis, R. Eric, Harrington, Melvyn A., Cahill, Catherine W., Bueso-Ramos, Carlos, Andreeff, Michael
Publicado no JCI Insight (2017)