AML-induced osteogenic differentiation in mesenchymal stromal cells supports leukemia growth

Genotypic and phenotypic alterations in the bone marrow (BM) microenvironment, in particular in osteoprogenitor cells, have been shown to support leukemogenesis. However, it is unclear how leukemia cells alter the BM microenvironment to create a hospitable niche. Here, we report that acute myeloid l...

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Detaylı Bibliyografya
Yayımlandı:JCI Insight
Asıl Yazarlar: Battula, V. Lokesh, Le, Phuong M., Sun, Jeffrey C., Nguyen, Khoa, Yuan, Bin, Zhou, Ximin, Sonnylal, Sonali, McQueen, Teresa, Ruvolo, Vivian, Michel, Keith A., Ling, Xiaoyang, Jacamo, Rodrigo, Shpall, Elizabeth, Wang, Zhiqiang, Rao, Arvind, Al-Atrash, Gheath, Konopleva, Marina, Davis, R. Eric, Harrington, Melvyn A., Cahill, Catherine W., Bueso-Ramos, Carlos, Andreeff, Michael
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Clinical Investigation 2017
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5499365/
https://ncbi.nlm.nih.gov/pubmed/28679949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.90036
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