AML-induced osteogenic differentiation in mesenchymal stromal cells supports leukemia growth

Genotypic and phenotypic alterations in the bone marrow (BM) microenvironment, in particular in osteoprogenitor cells, have been shown to support leukemogenesis. However, it is unclear how leukemia cells alter the BM microenvironment to create a hospitable niche. Here, we report that acute myeloid l...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:JCI Insight
Egile Nagusiak: Battula, V. Lokesh, Le, Phuong M., Sun, Jeffrey C., Nguyen, Khoa, Yuan, Bin, Zhou, Ximin, Sonnylal, Sonali, McQueen, Teresa, Ruvolo, Vivian, Michel, Keith A., Ling, Xiaoyang, Jacamo, Rodrigo, Shpall, Elizabeth, Wang, Zhiqiang, Rao, Arvind, Al-Atrash, Gheath, Konopleva, Marina, Davis, R. Eric, Harrington, Melvyn A., Cahill, Catherine W., Bueso-Ramos, Carlos, Andreeff, Michael
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Clinical Investigation 2017
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5499365/
https://ncbi.nlm.nih.gov/pubmed/28679949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.90036
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