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The CXCR4 Antagonist AMD3465 Regulates Oncogenic Signaling and Invasiveness In Vitro and Prevents Breast Cancer Growth and Metastasis In Vivo

CXCR4, the receptor for stromal-derived factor-1, is reportedly involved in breast carcinogenesis. However, the mechanisms through which CXCR4 contributes to breast cancer cell growth and metastases are poorly understood. In this study, we examined the putative in vitro and in vivo anti-cancer effec...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Ling, Xiaoyang, Spaeth, Erika, Chen, Ye, Shi, Yuexi, Zhang, Weiguo, Schober, Wendy, Hail, Numsen, Konopleva, Marina, Andreeff, Michael
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2013
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3590173/
https://ncbi.nlm.nih.gov/pubmed/23484027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0058426
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