AMD3465, a Novel CXCR4 Receptor Antagonist, Abrogates Schistosomal Antigen-Elicited (Type-2) Pulmonary Granuloma Formation

CXCR4 is a major receptor for CXCL12 and is known to participate in multiple physiological systems. The present study tested a second generation CXCR4 antagonist, AMD3465, for effects on highly defined models of Th1- and Th2-cell-mediated hypersensitivity-type pulmonary granuloma formation. Type-1 a...

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Bibliographische Detailangaben
Hauptverfasser: Hu, Jerry S., Freeman, Christine M., Stolberg, Valerie R., Chiu, Bo Chin, Bridger, Gary J., Fricker, Simon P., Lukacs, Nicholas W., Chensue, Stephen W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Investigative Pathology 2006
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Regular Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1599788/
https://ncbi.nlm.nih.gov/pubmed/16877345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2006.051234
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