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AMD3100, a CxCR4 Antagonist, Attenuates Allergic Lung Inflammation and Airway Hyperreactivity

The role of specific chemokine receptors during allergic asthmatic responses has been relatively undefined. A number of receptors are preferentially expressed on Th2 cells, including CCR4, CCR8, and CxCR4. In the present study, we have examined the role of CxCR4 in the development of cockroach aller...

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Bibliographic Details
Main Authors: Lukacs, Nicholas W., Berlin, Aaron, Schols, Dominique, Skerlj, Renato T., Bridger, Gary J.
Format: Artigo
Language:Inglês
Published: American Society for Investigative Pathology 2002
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1867206/
https://ncbi.nlm.nih.gov/pubmed/11943720
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