The CXCR4 Antagonist AMD3465 Regulates Oncogenic Signaling and Invasiveness In Vitro and Prevents Breast Cancer Growth and Metastasis In Vivo

par Ling, Xiaoyang, Spaeth, Erika, Chen, Ye, Shi, Yuexi, Zhang, Weiguo, Schober, Wendy, Hail, Numsen, Konopleva, Marina, Andreeff, Michael
Publié 2013

Targeting connective tissue growth factor (CTGF) in acute lymphoblastic leukemia pre-clinical models: anti-CTGF monoclonal antibody attenuates leukemia growth

par Lu, Hongbo, Kojima, Kensuke, Battula, Venkata Lokesh, Korchin, Borys, Shi, Yuexi, Chen, Ye, Spong, Suzanne, Thomas, Deborah A., Kantarjian, Hagop, Lock, Richard B, Andreeff, Michael, Konopleva, Marina
Publié 2013

Mesenchymal Stem Cells Overexpressing IFN-β Inhibit Breast Cancer Growth and Metastases through Stat3 Signaling in a Syngeneic Tumor Model

par Ling, Xiaoyang, Marini, Frank, Konopleva, Marina, Schober, Wendy, Shi, Yuexi, Burks, Jared, Clise-Dwyer, Karen, Wang, Rui-Yu, Zhang, Weiguo, Yuan, Xiaoqing, Lu, Hongbo, Caldwell, Lisa, Andreeff, Michael
Publié 2010

Epithelial-mesenchymal transition-derived cells exhibit multi-lineage differentiation potential similar to mesenchymal stem cells

par Battula, Venkata L., Evans, Kurt W., Hollier, Brett G., Shi, Yuexi, Marini, Frank C., Ayyanan, Ayyakkannu, Wang, Rui-Yu, Brisken, Cathrin, Guerra, Rudy, Andreeff, Michael, Mani, Sendurai A.
Publié 2010

Concomitant inhibition of DNA methyltransferase and BCL-2 protein function synergistically induce mitochondrial apoptosis in acute myelogenous leukemia cells

par Tsao, Twee, Shi, Yuexi, Kornblau, Steven, Lu, Hongbo, Konoplev, Sergej, Antony, Ansu, Ruvolo, Vivian, Qiu, Yi Hua, Zhang, Ninaxiang, Coombes, Kevin R., Andreeff, Michael, Kojima, Kensuke, Konopleva, Marina
Publié 2012

Ganglioside GD2 identifies breast cancer stem cells and promotes tumorigenesis

par Battula, Venkata Lokesh, Shi, Yuexi, Evans, Kurt W., Wang, Rui-Yu, Spaeth, Erika L., Jacamo, Rodrigo O., Guerra, Rudy, Sahin, Aysegul A., Marini, Frank C., Hortobagyi, Gabriel, Mani, Sendurai A., Andreeff, Michael
Publié 2012

Synergistic Targeting of AML Stem/Progenitor Cells With IAP Antagonist Birinapant and Demethylating Agents

par Carter, Bing Z., Mak, Po Yee, Mak, Duncan H., Shi, Yuexi, Qiu, Yihua, Bogenberger, James M., Mu, Hong, Tibes, Raoul, Yao, Hui, Coombes, Kevin R., Jacamo, Rodrigo O., McQueen, Teresa, Kornblau, Steven M., Andreeff, Michael
Publié 2014

Pronounced Hypoxia in Models of Murine and Human Leukemia: High Efficacy of Hypoxia-Activated Prodrug PR-104

par Benito, Juliana, Shi, Yuexi, Szymanska, Barbara, Carol, Hernan, Boehm, Ingrid, Lu, Hongbo, Konoplev, Sergej, Fang, Wendy, Zweidler-McKay, Patrick A., Campana, Dario, Borthakur, Gautam, Bueso-Ramos, Carlos, Shpall, Elizabeth, Thomas, Deborah A., Jordan, Craig T., Kantarjian, Hagop, Wilson, William R., Lock, Richard, Andreeff, Michael, Konopleva, Marina
Publié 2011

Hypoxia-activated prodrug TH-302 targets hypoxic bone marrow niches in pre-clinical leukemia models

par Benito, Juliana, Ramirez, Marc, Millward, Niki Zacharias, Velez, Juliana, Harutyunyan, Karine, Lu, Hongbo, Shi, Yuexi, Matre, Polina, Jacamo, Rodrigo, Ma, Helen, Konoplev, Sergej, McQueen, Teresa, Volgin, Andrei, Protopopova, Marina, Mu, Hong, Lee, Jaehyuk, Bhattacharya, Pratip, Marszalek, Joseph R, Davis, R. Eric, Bankson, Jim, Cortes, Jorge, Hart, Charles P, Andreeff, Michael, Konopleva, Marina
Publié dans Clin Cancer Res (2015)