Photoacoustic-based oxygen saturation assessment of murine femoral bone marrow in a preclinical model of leukemia

Por Wood, Cayla, Harutyunyan, Karine, Sampaio, Diego R.T., Konopleva, Marina, Bouchard, Richard
Publicado no Photoacoustics (2019)

Inhibition of Oxidative Phosphorylation Reverses Bone Marrow Hypoxia Visualized in Imageable Syngeneic B-ALL Mouse Model

Por Rytelewski, Mateusz, Harutyunyan, Karine, Baran, Natalia, Mallampati, Saradhi, Zal, M. Anna, Cavazos, Antonio, Butler, Jason M., Konoplev, Sergej, El Khatib, Mirna, Plunkett, Shane, Marszalek, Joseph R., Andreeff, Michael, Zal, Tomasz, Konopleva, Marina
Publicado no Front Oncol (2020)

Identification of a Novel C16orf57 Mutation in Athabaskan Patients with Poikiloderma with Neutropenia

Por Clericuzio, Carol, Harutyunyan, Karine, Jin, Weidong, Erickson, Robert P., Irvine, Alan D., McLean, W.H. Irwin, Wen, Yaran, Bagatell, Rochelle, Griffin, Thomas A., Shwayder, Tor A., Plon, Sharon E., Wang, Lisa L.
Publicado em 2010

A Phase I Study of Evofosfamide, an Investigational Hypoxia-Activated Prodrug, in Patients with Advanced Leukemia

Por Badar, Talha, Handisides, Damian R., Benito, Juliana M., Richie, Mary Ann, Borthakur, Gautam, Jabbour, Elias, Harutyunyan, Karine, Konoplev, Sergej, Faderl, Stefan, Kroll, Stew, Andreeff, Michael, Pearce, Tillman, Kantarjian, Hagop M., Cortes, Jorge E., Thomas, Deborah A., Konopleva, Marina
Publicado no Am J Hematol (2016)

Glutaminase activity of L-asparaginase contributes to durable preclinical activity against acute lymphoblastic leukemia

Por Chan, Wai Kin, Horvath, Thomas D., Tan, Lin, Link, Todd, Harutyunyan, Karine G., Pontikos, Michael A., Anishkin, Andriy, Du, Di, Martin, Leona A., Yin, Eric, Rempe, Susan B., Sukharev, Sergei, Konopleva, Marina, Weinstein, John N., Lorenzi, Philip L.
Publicado no Mol Cancer Ther (2019)

Hypoxia-activated prodrug TH-302 targets hypoxic bone marrow niches in pre-clinical leukemia models

Por Benito, Juliana, Ramirez, Marc, Millward, Niki Zacharias, Velez, Juliana, Harutyunyan, Karine, Lu, Hongbo, Shi, Yuexi, Matre, Polina, Jacamo, Rodrigo, Ma, Helen, Konoplev, Sergej, McQueen, Teresa, Volgin, Andrei, Protopopova, Marina, Mu, Hong, Lee, Jaehyuk, Bhattacharya, Pratip, Marszalek, Joseph R, Davis, R. Eric, Bankson, Jim, Cortes, Jorge, Hart, Charles P, Andreeff, Michael, Konopleva, Marina
Publicado no Clin Cancer Res (2015)

Spectrum of CHD7 Mutations in 110 Individuals with CHARGE Syndrome and Genotype-Phenotype Correlation

Por Lalani, Seema R., Safiullah, Arsalan M., Fernbach, Susan D., Harutyunyan, Karine G., Thaller, Christina, Peterson, Leif E., McPherson, John D., Gibbs, Richard A., White, Lisa D., Hefner, Margaret, Davenport, Sandra L. H., Graham, John M., Bacino, Carlos A., Glass, Nancy L., Towbin, Jeffrey A., Craigen, William J., Neish, Steven R., Lin, Angela E., Belmont, John W.
Publicado em 2006

Selective BCL-2 Inhibition by ABT-199 Causes On Target Cell Death in Acute Myeloid Leukemia

Por Pan, Rongqing, Hogdal, Leah J., Benito, Juliana M, Bucci, Donna, Han, Lina, Borthakur, Gautam, Cortes, Jorge, DeAngelo, Daniel J., Debose, LaKeisha, Mu, Hong, Döhner, Hartmut, Gaidzik, Verena I., Galinsky, Ilene, Golfman, Leonard S., Haferlach, Torsten, Harutyunyan, Karine G., Hu, Jianhua, Leverson, Joel D, Marcucci, Guido, Müschen, Markus, Newman, Rachel, Park, Eugene, Ruvolo, Peter P., Ruvolo, Vivian, Ryan, Jeremy, Schindela, Sonja, Zweidler-McKay, Patrick, Stone, Richard M., Kantarjian, Hagop, Andreeff, Michael, Konopleva, Marina, Letai, Anthony G.
Publicado em 2013

MLL-Rearranged Acute Lymphoblastic Leukemias Activate BCL-2 through H3K79 Methylation and Are Sensitive to the BCL-2-Specific Antagonist ABT-199

Por Benito, Juliana M., Godfrey, Laura, Kojima, Kensuke, Hogdal, Leah, Wunderlich, Mark, Geng, Huimin, Marzo, Isabel, Harutyunyan, Karine G., Golfman, Leonard, North, Phillip, Kerry, Jon, Ballabio, Erica, Chonghaile, Triona Ní, Gonzalo, Oscar, Qiu, Yihua, Jeremias, Irmela, Debose, LaKiesha, O’Brien, Eric, Ma, Helen, Zhou, Ping, Jacamo, Rodrigo, Park, Eugene, Coombes, Kevin R., Zhang, Nianxiang, Thomas, Deborah A., O’Brien, Susan, Kantarjian, Hagop M., Leverson, Joel D., Kornblau, Steven M., Andreeff, Michael, Müschen, Markus, Zweidler-McKay, Patrick A., Mulloy, James C., Letai, Anthony, Milne, Thomas A., Konopleva, Marina
Publicado no Cell Rep (2015)