p53 C-terminal interaction with DNA ends and gaps has opposing effect on specific DNA binding by the core

Por Zotchev, Sergey B., Protopopova, Marina, Selivanova, Galina
Publicado em 2000

Changes of cellular stress response related hsp70 and abcb1 transcript and Hsp70 protein levels in Siberian freshwater amphipods upon exposure to cadmium chloride in the lethal con...

Por Protopopova, Marina V., Pavlichenko, Vasiliy V., Luckenbach, Till
Publicado no PeerJ (2020)

Drug Therapy of Experimental Tuberculosis (TB): Improved Outcome by Combining SQ109, a New Diamine Antibiotic, with Existing TB Drugs

Por Nikonenko, Boris V., Protopopova, Marina, Samala, Rowena, Einck, Leo, Nacy, Carol A.
Publicado em 2007

Discovery and development of SQ109: a new antitubercular drug with a novel mechanism of action

Por Sacksteder, Katherine A, Protopopova, Marina, Barry, Clifton E, Andries, Koen, Nacy, Carol A
Publicado em 2012

Interspecies pharmacokinetics and in vitro metabolism of SQ109

Por Jia, Lee, Noker, Patricia E, Coward, Lori, Gorman, Gregory S, Protopopova, Marina, Tomaszewski, Joseph E
Publicado em 2006

Chemical modification of capuramycins to enhance antibacterial activity

Por Bogatcheva, Elena, Dubuisson, Tia, Protopopova, Marina, Einck, Leo, Nacy, Carol A., Reddy, Venkata M.
Publicado em 2011

Therapeutic Efficacy of SQ641-NE against Mycobacterium tuberculosis

Por Nikonenko, Boris, Reddy, Venkata M., Bogatcheva, Elena, Protopopova, Marina, Einck, Leo, Nacy, Carol A.
Publicado em 2014

Activity of SQ641, a Capuramycin Analog, in a Murine Model of Tuberculosis

Por Nikonenko, Boris V., Reddy, Venkata M., Protopopova, Marina, Bogatcheva, Elena, Einck, Leo, Nacy, Carol A.
Publicado em 2009

Discovery of dipiperidines as new antitubercular agents

Por Bogatcheva, Elena, Hanrahan, Colleen, Chen, Ping, Gearhart, Jacqueline, Sacksteder, Katherine, Einck, Leo, Nacy, Carol, Protopopova, Marina
Publicado em 2009

Pharmacodynamics and pharmacokinetics of SQ109, a new diamine-based antitubercular drug

Por Jia, Lee, Tomaszewski, Joseph E, Hanrahan, Colleen, Coward, Lori, Noker, Patricia, Gorman, Gregory, Nikonenko, Boris, Protopopova, Marina
Publicado em 2004

Identification of new diamine scaffolds with activity against Mycobacterium tuberculosis

Por Bogatcheva, Elena, Hanrahan, Colleen, Nikonenko, Boris, Samala, Rowena, Chen, Ping, Gearhart, Jacqueline, Barbosa, Francis, Einck, Leo, Nacy, Carol A., Protopopova, Marina
Publicado no J Med Chem (2006)

Identification of SQ609 as a lead compound from a library of dipiperidines

Por Bogatcheva, Elena, Hanrahan, Colleen, Nikonenko, Boris, de los Santos, Gladys, Reddy, Venkata, Chen, Ping, Barbosa, Francis, Einck, Leo, Nacy, Carol, Protopopova, Marina
Publicado em 2011

Treatment of Clostridium difficile infection using SQ641, a capuramycin analogue, increases post-treatment survival and improves clinical measures of disease in a murine model

Por Moore, John H., van Opstal, Edward, Kolling, Glynis L., Shin, Jae Hyun, Bogatcheva, Elena, Nikonenko, Boris, Einck, Leo, Phipps, Andrew J., Guerrant, Richard L., Protopopova, Marina, Warren, Cirle Alcantara
Publicado no J Antimicrob Chemother (2016)

Antileukemia activity of the novel peptidic CXCR4 antagonist LY2510924 as monotherapy and in combination with chemotherapy

Por Cho, Byung-Sik, Zeng, Zhihong, Mu, Hong, Wang, Zhiqiang, McQueen, Teresa, Protopopova, Marina, Cortes, Jorge, Marszalek, Joseph R., Peng, Sheng-Bin, Ma, Wencai, Davis, R. Eric, Thornton, Donald E., Andreeff, Michael, Konopleva, Marina
Publicado no Blood (2015)

The Differentiation and Stress Response Factor XBP-1 Drives Multiple Myeloma Pathogenesis

Por Carrasco, Daniel R., Sukhdeo, Kumar, Protopopova, Marina, Sinha, Raktim, Enos, Miriam, Carrasco, Daniel E., Zheng, Mei, Mani, Mala, Henderson, Joel, Pinkus, Geraldine S., Munshi, Nikhil, Horner, James, Ivanova, Elena V., Protopopov, Alexei, Anderson, Kenneth C., Tonon, Giovanni, DePinho, Ronald A.
Publicado em 2007

Hypoxia-activated prodrug TH-302 targets hypoxic bone marrow niches in pre-clinical leukemia models

Por Benito, Juliana, Ramirez, Marc, Millward, Niki Zacharias, Velez, Juliana, Harutyunyan, Karine, Lu, Hongbo, Shi, Yuexi, Matre, Polina, Jacamo, Rodrigo, Ma, Helen, Konoplev, Sergej, McQueen, Teresa, Volgin, Andrei, Protopopova, Marina, Mu, Hong, Lee, Jaehyuk, Bhattacharya, Pratip, Marszalek, Joseph R, Davis, R. Eric, Bankson, Jim, Cortes, Jorge, Hart, Charles P, Andreeff, Michael, Konopleva, Marina
Publicado no Clin Cancer Res (2015)

Genomic alterations link Rho family of GTPases to the highly invasive phenotype of pancreas cancer

Por Kimmelman, Alec C., Hezel, Aram F., Aguirre, Andrew J., Zheng, Hongwu, Paik, Ji-hye, Ying, Haoqiang, Chu, Gerald C., Zhang, Jean X., Sahin, Ergun, Yeo, Giminna, Ponugoti, Aditya, Nabioullin, Roustem, Deroo, Scott, Yang, Shenghong, Wang, Xiaoxu, McGrath, John P., Protopopova, Marina, Ivanova, Elena, Zhang, Jianhua, Feng, Bin, Tsao, Ming S., Redston, Mark, Protopopov, Alexei, Xiao, Yonghong, Futreal, P. Andrew, Hahn, William C., Klimstra, David S., Chin, Lynda, DePinho, Ronald A.
Publicado em 2008

Moving toward Tuberculosis Elimination. Critical Issues for Research in Diagnostics and Therapeutics for Tuberculosis Infection

Por Keshavjee, Salmaan, Amanullah, Farhana, Cattamanchi, Adithya, Chaisson, Richard, Dobos, Karen M., Fox, Gregory J., Gendelman, Howard E., Gordon, Richard, Hesseling, Anneke, Le Van, Hoi, Kampmann, Beate, Kana, Bavesh, Khuller, Gopal, Lewinsohn, David M., Lewinsohn, Deborah A., Lin, Philiana Ling, Lu, Lenette Lin, Maartens, Gary, Owen, Andrew, Protopopova, Marina, Rengarajan, Jyothi, Rubin, Eric, Salgame, Padmini, Schurr, Erwin, Seddon, James A., Swindells, Susan, Tobin, David M., Udwadia, Zarir, Walzl, Gerhard, Srinivasan, Sudha, Rustomjee, Roxana, Nahid, Payam
Publicado no Am J Respir Crit Care Med (2019)