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Therapeutic Efficacy of SQ641-NE against Mycobacterium tuberculosis
A phospholipid-based nanoemulsion formulation of SQ641 (SQ641-NE) was active against intracellular Mycobacterium tuberculosis in J774A.1 mouse macrophages, although SQ641 by itself was not. Intravenous (i.v.) SQ641-NE was cleared from circulation and reached peak concentrations in lung and spleen in...
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| Main Authors: | , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Society for Microbiology
2014
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3910727/ https://ncbi.nlm.nih.gov/pubmed/24145521 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01254-13 |
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