Identification of SQ609 as a lead compound from a library of dipiperidines

We recently reported that compounds created around a dipiperidine scaffold demonstrated activity against Mycobacterium tuberculosis (Mtb) (Bogatcheva, E.; Hanrahan, C.; Chen, P.; Gearhart, J.; Sacksteder, K.; Einck, L.; Nacy, C.; Protopopova, M. Bioorg. Med. Chem. Lett.2010, 20, 201). To optimize th...

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Bibliographic Details
Main Authors: Bogatcheva, Elena, Hanrahan, Colleen, Nikonenko, Boris, de los Santos, Gladys, Reddy, Venkata, Chen, Ping, Barbosa, Francis, Einck, Leo, Nacy, Carol, Protopopova, Marina
Format: Artigo
Language:Inglês
Published: 2011
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3173259/
https://ncbi.nlm.nih.gov/pubmed/21807506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2011.07.015
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