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Rapid, Simple In Vivo Screen for New Drugs Active against Mycobacterium tuberculosis

We evaluated the use of a simple and easy-to-obtain potential marker of tuberculosis (TB) drug efficacy, body weight, and correlated weight loss or gain with the number of CFU of Mycobacterium tuberculosis in lungs and spleens of infected mice. C3H mice were infected intravenously with 10(6) CFU of...

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Detalhes bibliográficos
Main Authors: Nikonenko, Boris V., Samala, Rowena, Einck, Leo, Nacy, Carol A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC529200/
https://ncbi.nlm.nih.gov/pubmed/15561824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.12.4550-4555.2004
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