Pharmacodynamics and pharmacokinetics of SQ109, a new diamine-based antitubercular drug

1. SQ109 is a novel [1,2]-diamine-based ethambutol (EMB) analog developed from high-throughput combinatorial screening. The present study aimed at characterizing its pharmacodynamics and pharmacokinetics. 2. The antimicrobial activity of SQ109 was confirmed in vitro (Mycobacterium tuberculosis-infec...

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Autori principali: Jia, Lee, Tomaszewski, Joseph E, Hanrahan, Colleen, Coward, Lori, Noker, Patricia, Gorman, Gregory, Nikonenko, Boris, Protopopova, Marina
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2004
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Papers
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1575972/
https://ncbi.nlm.nih.gov/pubmed/15644871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0705984
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