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Interspecies pharmacokinetics and in vitro metabolism of SQ109
1. This study aimed at characterizing the interspecies absorption, distribution, metabolism and elimination (ADME) profile of N-geranyl-N′-(2-adamantyl)ethane-1,2-diamine (SQ109), a new diamine-based antitubercular drug. 2. Single doses of SQ109 were administered (intravenously (i.v.) and per os (p....
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| Hlavní autoři: | , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Nature Publishing Group
2006
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1616981/ https://ncbi.nlm.nih.gov/pubmed/16432511 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706650 |
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