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A novel and rapid LC/MS/MS assay for bioanalysis of Azurin p28 in serum and its pharmacokinetics in mice

Azurin p28 (NSC745104) is a 28 amino acid peptide fragment that inhibits proliferation of human solid and hematological malignancies in vitro and in vivo by reducing proteasomal degradation of oncogene p53. The present study aimed at developing a novel and fast liquid chromatography/tandem mass spec...

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Main Authors: Gorman, Greg S., Coward, Lori U., Freeman, Lea, Noker, Pat E., Beattie, Craig W., Jia, Lee
Formato: Artigo
Idioma:Inglês
Publicado: 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2922440/
https://ncbi.nlm.nih.gov/pubmed/20638810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpba.2010.06.006
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