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Chemical modification of capuramycins to enhance antibacterial activity
OBJECTIVES: To extend capuramycin spectrum of activity beyond mycobacteria and improve intracellular drug activity. METHODS: Three capuramycin analogues (SQ997, SQ922 and SQ641) were conjugated with different natural and unnatural amino acids or decanoic acid (DEC) through an ester bond at one or mo...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3037154/ https://ncbi.nlm.nih.gov/pubmed/21186194 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dkq495 |
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