Mimicking the BH3 domain to kill cancer cells

Por Chonghaile, Triona Ni, Letai, Anthony
Publicado em 2008

Who Put the “A” in Atg12: Autophagy or Apoptosis?

Por Chonghaile, Triona Ni, Letai, Anthony
Publicado em 2011

Mitochondria: gatekeepers of response to chemotherapy

Por Sarosiek, Kristopher A., Chonghaile, Triona Ni, Letai, Anthony
Publicado em 2013

Distinct mechanisms of cardiomyocyte apoptosis induced by doxorubicin and hypoxia converge on mitochondria and are inhibited by Bcl-xL

Por Reeve, Janice LV, Szegezdi, Eva, Logue, Susan E, Chonghaile, Tríona Ní, O’Brien, Timothy, Ritter, Thomas, Samali, Afshin
Publicado em 2007

BH3-profiling identifies heterogeneous dependency on Bcl-2 family members in Multiple Myeloma and predicts sensitivity to BH3 mimetics

Por Touzeau, Cyrille, Ryan, Jeremy, Guerriero, Jennifer L., Moreau, Philippe, Chonghaile, Triona Ni, Gouill, Steven Le, Richardson, Paul, Anderson, Kenneth, Amiot, Martine, Letai, Anthony
Publicado no Leukemia (2015)

Maturation Stage of T-cell Acute Lymphoblastic Leukemia Determines BCL-2 versus BCL-XL Dependence and Sensitivity to ABT-199

Por Chonghaile, Triona Ni, Roderick, Justine E., Glenfield, Cian, Ryan, Jeremy, Sallan, Stephen E., Silverman, Lewis B., Loh, Mignon L., Hunger, Stephen P., Wood, Brent, DeAngelo, Daniel J., Stone, Richard, Harris, Marian, Gutierrez, Alejandro, Kelliher, Michelle A., Letai, Anthony
Publicado em 2014

Cell and Molecular Determinants of In Vivo Efficacy of the BH3 Mimetic ABT-263 Against Pediatric Acute Lymphoblastic Leukemia Xenografts

Por Suryani, Santi, Carol, Hernan, Chonghaile, Triona Ni, Frismantas, Viktoras, Sarmah, Chintanu, High, Laura, Bornhauser, Beat, Cowley, Mark J, Szymanska, Barbara, Evans, Kathryn, Boehm, Ingrid, Tonna, Elise, Jones, Luke, Manesh, Donya Moradi, Kurmasheva, Raushan T., Billups, Catherine, Kaplan, Warren, Letai, Anthony, Bourquin, Jean-Pierre, Houghton, Peter J, Smith, Malcolm A, Lock, Richard B
Publicado em 2014

Pretreatment Mitochondrial Priming Correlates with Clinical Response to Cytotoxic Chemotherapy

Por Chonghaile, Triona Ni, Sarosiek, Kristopher A., Vo, Thanh-Trang, Ryan, Jeremy A., Tammareddi, Anupama, Moore, Victoria Del Gaizo, Deng, Jing, Anderson, Ken, Richardson, Paul, Tai, Yu-Tzu, Mitsiades, Constantine S., Matulonis, Ursula A., Drapkin, Ronny, Stone, Richard, DeAngelo, Daniel J., McConkey, David J., Sallan, Stephen E., Silverman, Lewis, Hirsch, Michelle S., Carrasco, Daniel Ruben, Letai, Anthony
Publicado em 2011

MLL-Rearranged Acute Lymphoblastic Leukemias Activate BCL-2 through H3K79 Methylation and Are Sensitive to the BCL-2-Specific Antagonist ABT-199

Por Benito, Juliana M., Godfrey, Laura, Kojima, Kensuke, Hogdal, Leah, Wunderlich, Mark, Geng, Huimin, Marzo, Isabel, Harutyunyan, Karine G., Golfman, Leonard, North, Phillip, Kerry, Jon, Ballabio, Erica, Chonghaile, Triona Ní, Gonzalo, Oscar, Qiu, Yihua, Jeremias, Irmela, Debose, LaKiesha, O’Brien, Eric, Ma, Helen, Zhou, Ping, Jacamo, Rodrigo, Park, Eugene, Coombes, Kevin R., Zhang, Nianxiang, Thomas, Deborah A., O’Brien, Susan, Kantarjian, Hagop M., Leverson, Joel D., Kornblau, Steven M., Andreeff, Michael, Müschen, Markus, Zweidler-McKay, Patrick A., Mulloy, James C., Letai, Anthony, Milne, Thomas A., Konopleva, Marina
Publicado no Cell Rep (2015)