The integrated stress response and proteotoxicity in cancer therapy

Por McConkey, David J.
Publicado no Biochem Biophys Res Commun (2017)

The transcriptional repressor Delta EF1 controls the EMT phenotype and resistance to the EGFR inhibitor erlotinib in human head & neck squamous cell carcinoma lines

Por Haddad, Yasmine, Choi, Woonyoung, McConkey, David J.
Publicado em 2009

Proteasome inhibitors activate autophagy as a cytoprotective response in human prostate cancer cells

Por Zhu, Keyi, Dunner, Kenneth, McConkey, David J
Publicado em 2009

Nitric Oxide–Dependent Activation of P53 Suppresses Bleomycin-Induced Apoptosis in the Lung

Por Davis, Darren W., Weidner, Douglas A., Holian, Andrij, McConkey, David J.
Publicado em 2000

Measuring soluble forms of extracellular cytokeratin 18 identifies both apoptotic and necrotic mechanisms of cell death produced by adenoviral-mediated interferon α: possible use a...

Por Fisher, Mark, Zhang, Xin-qiao, McConkey, David J., Benedict, William F.
Publicado em 2009

Control of HIF-1α expression by eIF2α phosphorylation mediated translational repression

Por Zhu, Keyi, Chan, WaiKin, Heymach, John, Wilkinson, Miles, McConkey, David J
Publicado em 2009

Fibroblast Growth Factor Receptors-1 and -3 Play Distinct Roles in the Regulation of Bladder Cancer Growth and Metastasis: Implications for Therapeutic Targeting

Por Cheng, Tiewei, Roth, Beat, Choi, Woonyoung, Black, Peter C., Dinney, Colin, McConkey, David J.
Publicado em 2013

Targeting endoplasmic reticulum protein transport: a novel strategy to kill malignant B cells and overcome fludarabine resistance in CLL

Por Carew, Jennifer S., Nawrocki, Steffan T., Krupnik, Yelena V., Dunner, Kenneth, McConkey, David J., Keating, Michael J., Huang, Peng
Publicado em 2006

NPI-0052, a novel proteasome inhibitor, induces caspase-8 and ROS-dependent apoptosis alone and in combination with HDAC inhibitors in leukemia cells

Por Miller, Claudia P., Ban, Kechen, Dujka, Melanie E., McConkey, David J., Munsell, Mark, Palladino, Michael, Chandra, Joya
Publicado em 2007

Autophagy limits the cytotoxic effects of the AKT inhibitor AZ7328 in human bladder cancer cells

Por Dickstein, Rian J., Nitti, Giovanni, Dinney, Colin P., Davies, Barry R., Kamat, Ashish M., McConkey, David J.
Publicado em 2012

Inhibition of Inducible Heat Shock Protein-70 (Hsp72) Enhances Bortezomib-Induced Cell Death in Human Bladder Cancer Cells

Por Qi, Wei, White, Matthew C., Choi, Woonyoung, Guo, Charles, Dinney, Colin, McConkey, David J., Siefker-Radtke, Arlene
Publicado em 2013

A Smac mimetic augments the response of urothelial cancer cells to gemcitabine and cisplatin

Por Lee, Eugene K, Jinesh G, Goodwin, Laing, Naomi M, Choi, Woonyoung, McConkey, David J, Kamat, Ashish M
Publicado em 2013

Specific micro-RNA expression patterns distinguish the basal and luminal subtypes of muscle-invasive bladder cancer

Por Ochoa, Andrea E., Choi, Woonyoung, Su, Xiaoping, Siefker-Radtke, Arlene, Czerniak, Bogdan, Dinney, Colin, McConkey, David J.
Publicado no Oncotarget (2016)

Caspase-Dependent Apoptosis Induced by Telomere Cleavage and TRF2 Loss

Por Multani, Asha S, Ozen, Mustafa, Narayan, Satya, Kumar, Virendra, Chandra, Joya, McConkey, David J, Newman, Robert A, Pathak, Sen
Publicado em 2000

Early RB94 Produced Cytotoxicity Is Independent of Caspase Activation and 50 kb DNA Fragmentation

Por Zhou, Jain, Zhang, Xin-qiao, Ashoori, Faramarz, McConkey, David J., Knowles, Margaret A., Dong, Li, Benedict, William F.
Publicado em 2008

Cis-urocanic acid, a sunlight-induced immunosuppressive factor, activates immune suppression via the 5-HT(2A) receptor

Por Walterscheid, Jeffrey P., Nghiem, Dat X., Kazimi, Nasser, Nutt, Leta K., McConkey, David J., Norval, Mary, Ullrich, Stephen E.
Publicado em 2006

Disruption of Mekk2 in Mice Reveals an Unexpected Role for MEKK2 in Modulating T-Cell Receptor Signal Transduction

Por Guo, Zijian, Clydesdale, Gavin, Cheng, Jinke, Kim, Kihwan, Gan, Lin, McConkey, David J., Ullrich, Stephen E., Zhuang, Yuan, Su, Bing
Publicado em 2002

Molecular genetics of bladder cancer: Emerging mechanisms of tumor initiation and progression

Por McConkey, David J., Lee, Sangkyou, Choi, Woonyoung, Tran, Mai, Majewski, Tadeusz, Lee, Sooyong, Siefker-Radtke, Arlene, Dinney, Colin, Czerniak, Bogdan
Publicado em 2010

p63 expression correlates with sensitivity to the Eg5 inhibitor AZD4877 in bladder cancer cells

Por Marquis, Lauren, Tran, Mai, Choi, Woonyoung, Lee, I-ling, Huszar, Dennis, Siefker-Radtke, Arlene, Dinney, Colin P., McConkey, David J.
Publicado em 2012

Bladder Cancer Molecular Taxonomy: Summary from a Consensus Meeting

Por Lerner, Seth P., McConkey, David J., Hoadley, Katherine A., Chan, Keith S., Kim, William Y., Radvanyi, François, Höglund, Mattias, Real, Francisco X.
Publicado no Bladder Cancer (2016)