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Autophagy limits the cytotoxic effects of the AKT inhibitor AZ7328 in human bladder cancer cells
Background: Mutations that activate the PI3K/AKT/mTOR pathway are relatively common in urothelial (bladder) cancers, but how these pathway mutations affect AKT dependency is not known. We characterized the relationship between AKT pathway mutational status and sensitivity to the effects of the selec...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Landes Bioscience
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3493441/ https://ncbi.nlm.nih.gov/pubmed/22895070 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.21793 |
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