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The integrated stress response and proteotoxicity in cancer therapy

A variety of different forms of cellular stress can cause protein misfolding and aggregation and proteotoxicity. The cytoprotective response to proteotoxicity is termed the integrated stress response and involves 4 distinct serine/threonine protein kinases that converge on the translation initiation...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Biochem Biophys Res Commun
Egile nagusia: McConkey, David J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2017
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5319732/
https://ncbi.nlm.nih.gov/pubmed/28212730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2016.11.047
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