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The integrated stress response and proteotoxicity in cancer therapy
A variety of different forms of cellular stress can cause protein misfolding and aggregation and proteotoxicity. The cytoprotective response to proteotoxicity is termed the integrated stress response and involves 4 distinct serine/threonine protein kinases that converge on the translation initiation...
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| Published in: | Biochem Biophys Res Commun |
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| Main Author: | |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2017
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5319732/ https://ncbi.nlm.nih.gov/pubmed/28212730 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2016.11.047 |
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