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The integrated stress response and proteotoxicity in cancer therapy

A variety of different forms of cellular stress can cause protein misfolding and aggregation and proteotoxicity. The cytoprotective response to proteotoxicity is termed the integrated stress response and involves 4 distinct serine/threonine protein kinases that converge on the translation initiation...

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Bibliografski detalji
Izdano u:Biochem Biophys Res Commun
Glavni autor: McConkey, David J.
Format: Artigo
Jezik:Inglês
Izdano: 2017
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5319732/
https://ncbi.nlm.nih.gov/pubmed/28212730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2016.11.047
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