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Proteasome inhibitors activate autophagy as a cytoprotective response in human prostate cancer cells

The ubiquitin-proteasome and lysosome-autophagy pathways are the two major intracellular protein degradation systems that work cooperatively to maintain homeostasis. Proteasome inhibitors (PIs) have clinical activity in hematological tumors, and inhibitors of autophagy are also being evaluated as po...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Zhu, Keyi, Dunner, Kenneth, McConkey, David J
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2009
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2809784/
https://ncbi.nlm.nih.gov/pubmed/19881538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2009.343
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