Inhibition of Inducible Heat Shock Protein-70 (Hsp72) Enhances Bortezomib-Induced Cell Death in Human Bladder Cancer Cells

The proteasome inhibitor bortezomib (Velcade) is a promising new agent for bladder cancer therapy, but inducible cytoprotective mechanisms may limit its potential efficacy. We used whole genome mRNA expression profiling to study the effects of bortezomib on stress-induced gene expression in a panel...

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Main Authors: Qi, Wei, White, Matthew C., Choi, Woonyoung, Guo, Charles, Dinney, Colin, McConkey, David J., Siefker-Radtke, Arlene
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2013
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3715471/
https://ncbi.nlm.nih.gov/pubmed/23874968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0069509
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