Mitochondrial defects in cancer

Por Carew Jennifer S, Huang Peng
Publicado em 2002-12-01

Mitochondrial defects in cancer

Por Carew, Jennifer S, Huang, Peng
Publicado em 2002

Drain the lysosome: Development of the novel orally available autophagy inhibitor ROC-325

Por Carew, Jennifer S., Nawrocki, Steffan T.
Publicado no Autophagy (2017)

Autophagy: New Insights into Its Roles in Cancer Progression and Drug Resistance

Por Nawrocki, Steffan T., Wang, Wei, Carew, Jennifer S.
Publicado no Cancers (Basel) (2020)

Autophagy as a target for cancer therapy: new developments

Por Carew, Jennifer S, Kelly, Kevin R, Nawrocki, Steffan T
Publicado em 2012

Therapeutic Targeting of Autophagy for Renal Cell Carcinoma Therapy

Por Jones, Trace M., Carew, Jennifer S., Nawrocki, Steffan T.
Publicado no Cancers (Basel) (2020)

Targeting autophagy: a novel anticancer strategy with therapeutic implications for imatinib resistance

Por Carew, Jennifer S, Nawrocki, Steffan T, Giles, Francis J, Cleveland, John L
Publicado em 2008

Nilotinib: optimal therapy for patients with chronic myeloid leukemia and resistance or intolerance to imatinib

Por Swords, Ronan, Mahalingam, Devalingam, Padmanabhan, Swaminathan, Carew, Jennifer, Giles, Francis
Publicado em 2009

Moving beyond hydroxychloroquine: the novel lysosomal autophagy inhibitor ROC-325 shows significant potential in preclinical studies

Por Jones, Trace M., Espitia, Claudia, Wang, Wei, Nawrocki, Steffan T., Carew, Jennifer S.
Publicado no Cancer Commun (Lond) (2019)

Oncolytic Viruses for Multiple Myeloma Therapy

Por Calton, Christine M., Kelly, Kevin R., Anwer, Faiz, Carew, Jennifer S., Nawrocki, Steffan T.
Publicado no Cancers (Basel) (2018)

Resistance to histone deacetylase inhibitors confers hypersensitivity to oncolytic reovirus therapy

Por Islam, Shariful, Espitia, Claudia M., Persky, Daniel O., Carew, Jennifer S., Nawrocki, Steffan T.
Publicado no Blood Adv (2020)

Disruption of autophagic degradation with ROC-325 antagonizes renal cell carcinoma pathogenesis

Por Carew, Jennifer S., Espitia, Claudia M., Zhao, William, Han, Yingchun, Visconte, Valeria, Phillips, James, Nawrocki, Steffan T.
Publicado no Clin Cancer Res (2016)

Oncolytic reovirus inhibits angiogenesis through induction of CXCL10/IP-10 and abrogation of HIF activity in soft tissue sarcomas

Por Carew, Jennifer S., Espitia, Claudia M., Zhao, Weiguo, Mita, Monica M., Mita, Alain C., Nawrocki, Steffan T.
Publicado no Oncotarget (2017)

Rational cotargeting of HDAC6 and BET proteins yields synergistic antimyeloma activity

Por Carew, Jennifer S., Espitia, Claudia M., Zhao, Weiguo, Visconte, Valeria, Anwer, Faiz, Kelly, Kevin R., Nawrocki, Steffan T.
Publicado no Blood Adv (2019)

Novel role of p53 in maintaining mitochondrial genetic stability through interaction with DNA Pol γ

Por Achanta, Geetha, Sasaki, Ryohei, Feng, Li, Carew, Jennifer S, Lu, Weiqin, Pelicano, Helene, Keating, Michael J, Huang, Peng
Publicado em 2005

Targeting endoplasmic reticulum protein transport: a novel strategy to kill malignant B cells and overcome fludarabine resistance in CLL

Por Carew, Jennifer S., Nawrocki, Steffan T., Krupnik, Yelena V., Dunner, Kenneth, McConkey, David J., Keating, Michael J., Huang, Peng
Publicado em 2006

The novel Aurora A kinase inhibitor MLN8237 is active in resistant chronic myeloid leukaemia and significantly increases the efficacy of nilotinib

Por Kelly, Kevin R, Ecsedy, Jeffrey, Medina, Ernest, Mahalingam, Devalingam, Padmanabhan, Swaminathan, Nawrocki, Steffan T, Giles, Francis J, Carew, Jennifer S
Publicado no J Cell Mol Med (2011)

Junctional adhesion molecule-A is overexpressed in advanced multiple myeloma and determines response to oncolytic reovirus

Por Kelly, Kevin R., Espitia, Claudia M., Zhao, Weiguo, Wendlandt, Erik, Tricot, Guido, Zhan, Fenghuang, Carew, Jennifer S., Nawrocki, Steffan T.
Publicado no Oncotarget (2015)

Heightened JNK Activation and Reduced XIAP Levels Promote TRAIL and Sunitinib-Mediated Apoptosis in Colon Cancer Models

Por Mahalingam, Devalingam, Carew, Jennifer S., Espitia, Claudia M., Cool, Robbert H., Giles, Francis J., de Jong, Steven, Nawrocki, Steffan T.
Publicado no Cancers (Basel) (2019)

Lucanthone Is a Novel Inhibitor of Autophagy That Induces Cathepsin D-mediated Apoptosis

Por Carew, Jennifer S., Espitia, Claudia M., Esquivel, Juan A., Mahalingam, Devalingam, Kelly, Kevin R., Reddy, Guru, Giles, Francis J., Nawrocki, Steffan T.
Publicado em 2011