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Targeting autophagy: a novel anticancer strategy with therapeutic implications for imatinib resistance

Autophagy is an ancient, intracellular degradative system which plays important roles in regulating protein homeostasis and which is essential for survival when cells are faced with metabolic stress. Increasing evidence suggests that autophagy also functions as a tumor suppressor mechanism that harn...

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Detalhes bibliográficos
Main Authors: Carew, Jennifer S, Nawrocki, Steffan T, Giles, Francis J, Cleveland, John L
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2721364/
https://ncbi.nlm.nih.gov/pubmed/19707354
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