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Autophagy as a target for cancer therapy: new developments

Autophagy is an evolutionarily conserved lysosomal degradation pathway that eliminates cytosolic proteins, macromolecules, organelles, and protein aggregates. Activation of autophagy may function as a tumor suppressor by degrading defective organelles and other cellular components. However, this pat...

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Autori principali: Carew, Jennifer S, Kelly, Kevin R, Nawrocki, Steffan T
Natura: Artigo
Lingua:Inglês
Pubblicazione: Dove Medical Press 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3474143/
https://ncbi.nlm.nih.gov/pubmed/23091399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CMAR.S26133
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