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Early RB94 Produced Cytotoxicity Is Independent of Caspase Activation and 50 kb DNA Fragmentation
RB94, which lacks the NH2-terminal 112 amino acid residues of the full-length RB (RB110) is a more potent inhibitor of cancer cell growth than RB 110, being cytotoxic to all cancer cell lines studied, independent of their genetic abnormalities. Although we initially thought RB94 induced cell death w...
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| Главные авторы: | , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2008
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3090001/ https://ncbi.nlm.nih.gov/pubmed/18654611 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cgt.2008.54 |
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