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Tumor-targeting Nanocomplex Delivery of Tumor Suppressor RB94 Chemosensitizes Bladder Carcinoma Cells In Vitro and In Vivo

PURPOSE: RB94, a truncated form of RB110, has enhanced tumor suppressor potency and activity against all tumor types tested to date, including bladder carcinoma. However, efficient, systemic delivery of the gene encoding RB94 specifically to tumors is an obstacle to clinical application as an anti-c...

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Detalhes bibliográficos
Publicado no:Clin Cancer Res
Main Authors: Pirollo, Kathleen F., Rait, Antonina, Zhou, Qi, Zhang, Xin-qiao, Zhou, Jain, Kim, Chang-Soo, Benedict, William F., Chang, Esther H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4448145/
https://ncbi.nlm.nih.gov/pubmed/18381961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-07-1951
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