Tumor-targeting, systemically delivered antisense HER-2 chemosensitizes human breast cancer xenografts irrespective of HER-2 levels.

BACKGROUND: The failure to respond to chemotherapy is a major obstacle in the successful treatment of breast cancer. We have previously shown that anti-HER-2 antisense oligonucleotide (AS HER-2 ODN) treatment was able to sensitize breast cancer cells to various chemotherapeutic agents in vitro irres...

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Bibliografiska uppgifter
Huvudupphovsmän: Rait, Antonina S., Pirollo, Kathleen F., Xiang, Laiman, Ulick, David, Chang, Esther H.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2002
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2040013/
https://ncbi.nlm.nih.gov/pubmed/12435858
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