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Targeted nanocomplex carrying siRNA against MALAT1 sensitizes glioblastoma to temozolomide

Intrinsic therapeutic resistance especially in cancer stem cells (CSCs) together with extensive tumor cell infiltration and restricted permeation of the blood-brain barrier (BBB) by drugs may all contribute to the treatment failure in patients with glioblastoma multiforme (GBM). Accumulating evidenc...

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Foilsithe in:Nucleic Acids Res
Main Authors: Kim, Sang-Soo, Harford, Joe B, Moghe, Manish, Rait, Antonina, Pirollo, Kathleen F, Chang, Esther H
Formáid: Artigo
Teanga:Inglês
Foilsithe: Oxford University Press 2018
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5815062/
https://ncbi.nlm.nih.gov/pubmed/29202181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx1221
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