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Targeted nanocomplex carrying siRNA against MALAT1 sensitizes glioblastoma to temozolomide

Intrinsic therapeutic resistance especially in cancer stem cells (CSCs) together with extensive tumor cell infiltration and restricted permeation of the blood-brain barrier (BBB) by drugs may all contribute to the treatment failure in patients with glioblastoma multiforme (GBM). Accumulating evidenc...

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Bibliografski detalji
Izdano u:Nucleic Acids Res
Glavni autori: Kim, Sang-Soo, Harford, Joe B, Moghe, Manish, Rait, Antonina, Pirollo, Kathleen F, Chang, Esther H
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2018
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5815062/
https://ncbi.nlm.nih.gov/pubmed/29202181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx1221
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