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Anti-epidermal growth factor receptor siRNA carried by chitosan-transacylated lipid nanocapsules increases sensitivity of glioblastoma cells to temozolomide

Epidermal growth factor receptor (EGFR) is a crucial protein that plays an important role in the maintenance and development of glioblastomas. The silencing or knockdown of EGFR is possible by administering a small interfering ribonucleic acid (siRNA). Lipid nanocapsules (LNCs) covered by chitosan w...

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Detalhes bibliográficos
Main Authors: Messaoudi, Khaled, Saulnier, Patrick, Boesen, Kim, Benoit, Jean-Pierre, Lagarce, Frederic
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3969342/
https://ncbi.nlm.nih.gov/pubmed/24711698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S59134
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