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Development of streptavidin-based nanocomplex for siRNA delivery

In our previous study, we have identified a PCBP2 siRNA that exhibits antifibrotic activity in rat hepatic stellate cells (HSCs) by inhibition of αCP2, a protein responsible for stabilization of the collagen α1 (I) mRNA in alcoholic liver fibrosis. This study aims to develop a streptavidin-based nan...

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Detalhes bibliográficos
Main Authors: Shukla, Ravi S., Tai, Wanyi, Mahato, Rubi, Jin, Wei, Cheng, Kun
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3925747/
https://ncbi.nlm.nih.gov/pubmed/24160908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp400355q
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