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Development of a Peptide-Modified siRNA Nanocomplex for Hepatic Stellate Cells

Insulin-like growth factor 2 receptor (IGF2R) is overexpressed in activated Hepatic stellate cells (HSCs) and therefore can be utilized for HSC-specific drug delivery. We recently discovered an IGF2R-specific peptide using a novel biopanning. Here, we adopted biotin-conjugated IGF2R-specific peptide...

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書誌詳細
出版年:Nanomedicine
主要な著者: Zhao, Zhen, Li, Yuanke, Jain, Akshay, Chen, Zhijin, Liu, Hao, Jin, Wei, Cheng, Kun
フォーマット: Artigo
言語:Inglês
出版事項: 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5742024/
https://ncbi.nlm.nih.gov/pubmed/28890106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nano.2017.08.017
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