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Development of a Peptide-Modified siRNA Nanocomplex for Hepatic Stellate Cells

Insulin-like growth factor 2 receptor (IGF2R) is overexpressed in activated Hepatic stellate cells (HSCs) and therefore can be utilized for HSC-specific drug delivery. We recently discovered an IGF2R-specific peptide using a novel biopanning. Here, we adopted biotin-conjugated IGF2R-specific peptide...

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Bibliografske podrobnosti
izdano v:Nanomedicine
Main Authors: Zhao, Zhen, Li, Yuanke, Jain, Akshay, Chen, Zhijin, Liu, Hao, Jin, Wei, Cheng, Kun
Format: Artigo
Jezik:Inglês
Izdano: 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5742024/
https://ncbi.nlm.nih.gov/pubmed/28890106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nano.2017.08.017
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