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Co-delivery of IKBKE siRNA and cabazitaxel by hybrid nanocomplex inhibits invasiveness and growth of triple-negative breast cancer

IKBKE is an oncogene in triple-negative breast cancer (TNBC), and we demonstrate that IKBKE small interfering RNA (siRNA) inhibits the proliferation, migration, and invasion of TNBC cells. Despite the recent success of siRNA therapeutics targeting to the liver, there still remains a great challenge...

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Detaylı Bibliyografya
Yayımlandı:Sci Adv
Asıl Yazarlar: Zhao, Zhen, Li, Yuanke, Liu, Hao, Jain, Akshay, Patel, Pratikkumar Vinodchandra, Cheng, Kun
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Association for the Advancement of Science 2020
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7439402/
https://ncbi.nlm.nih.gov/pubmed/32832636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.abb0616
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