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FRET-Labeled siRNA Probes for Tracking Assembly and Disassembly of siRNA-Nanocomplexes

The assembly, stability and timely disassembly of short interfering RNA (siRNA) nanocomplexes all have the potential to affect the efficiency of siRNA delivery and gene silencing. As such, the design of new probes that can measure these properties without significantly perturbing the nanocomplexes o...

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Autors principals: Alabi, Christopher A., Love, Kevin T., Sahay, Gaurav, Stutzman, Tina, Young, Whitney T., Langer, Robert, Anderson, Daniel G.
Format: Artigo
Idioma:Inglês
Publicat: 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3404193/
https://ncbi.nlm.nih.gov/pubmed/22693946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/nn3013838
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