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Multiparametric approach for the evaluation of lipid nanoparticles for siRNA delivery

Nanoparticle-mediated siRNA delivery is a complex process that requires transport across numerous extracellular and intracellular barriers. As such, the development of nanoparticles for efficient delivery would benefit from an understanding of how parameters associated with these barriers relate to...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Alabi, Christopher A., Love, Kevin T., Sahay, Gaurav, Yin, Hao, Luly, Kathryn M., Langer, Robert, Anderson, Daniel G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3740846/
https://ncbi.nlm.nih.gov/pubmed/23882076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1306529110
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