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Development of siRNA-probes for studying intracellular trafficking of siRNA nanoparticles

One important barrier facing the delivery of short interfering RNAs (siRNAs) via synthetic nanoparticles is the rate of nanoparticle disassembly. However, our ability to optimize the release kinetics of siRNAs from nanoparticles for maximum efficacy is limited by the lack of methods to track their i...

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Detalhes bibliográficos
Main Authors: Alabi, Christopher A., Sahay, Gaurav, Langer, Robert, Anderson, Daniel G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3524365/
https://ncbi.nlm.nih.gov/pubmed/23014672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c2ib20155k
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