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Multiparametric approach for the evaluation of lipid nanoparticles for siRNA delivery

Nanoparticle-mediated siRNA delivery is a complex process that requires transport across numerous extracellular and intracellular barriers. As such, the development of nanoparticles for efficient delivery would benefit from an understanding of how parameters associated with these barriers relate to...

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Bibliografiske detaljer
Main Authors: Alabi, Christopher A., Love, Kevin T., Sahay, Gaurav, Yin, Hao, Luly, Kathryn M., Langer, Robert, Anderson, Daniel G.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3740846/
https://ncbi.nlm.nih.gov/pubmed/23882076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1306529110
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