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Multiparametric approach for the evaluation of lipid nanoparticles for siRNA delivery

Nanoparticle-mediated siRNA delivery is a complex process that requires transport across numerous extracellular and intracellular barriers. As such, the development of nanoparticles for efficient delivery would benefit from an understanding of how parameters associated with these barriers relate to...

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Main Authors: Alabi, Christopher A., Love, Kevin T., Sahay, Gaurav, Yin, Hao, Luly, Kathryn M., Langer, Robert, Anderson, Daniel G.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3740846/
https://ncbi.nlm.nih.gov/pubmed/23882076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1306529110
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