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Apoptotic death in epithelial cells: cleavage of DNA to 300 and/or 50 kb fragments prior to or in the absence of internucleosomal fragmentation.

To date, apoptosis has been characterized biochemically by the production of 180-200 bp internucleosomal DNA fragments resulting from the activation of an endonuclease(s). The principal morphological feature of apoptosis is the condensation of chromatin and it has been assumed that this may reflect...

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Autors principals: Oberhammer, F, Wilson, J W, Dive, C, Morris, I D, Hickman, J A, Wakeling, A E, Walker, P R, Sikorska, M
Format: Artigo
Idioma:Inglês
Publicat: 1993
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC413644/
https://ncbi.nlm.nih.gov/pubmed/8253089
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