DNase γ Is the Effector Endonuclease for Internucleosomal DNA Fragmentation in Necrosis

Apoptosis and necrosis, two major forms of cell death, can be distinguished morphologically and biochemically. Internucleosomal DNA fragmentation (INDF) is a biochemical hallmark of apoptosis, and caspase-activated DNase (CAD), also known as DNA fragmentation factor 40 kDa (DFF40), is one of the maj...

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Detalhes bibliográficos
Main Authors: Mizuta, Ryushin, Araki, Shinsuke, Furukawa, Makoto, Furukawa, Yuki, Ebara, Syota, Shiokawa, Daisuke, Hayashi, Katsuhiko, Tanuma, Sei-ichi, Kitamura, Daisuke
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3846476/
https://ncbi.nlm.nih.gov/pubmed/24312463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0080223
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