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Identification of two functional nuclear localization signals in DNase gamma and their roles in its apoptotic DNase activity.

Among DNase I family members, only DNase gamma causes DNA fragmentation during apoptosis. However, the molecular basis for this functional feature of DNase gamma is poorly understood. Here we describe the identification of functional NLSs (nuclear localization signals) in DNase gamma and their roles...

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Detalhes bibliográficos
Main Authors: Shiokawa, Daisuke, Shika, Yukari, Tanuma, Sei-ichi
Formato: Artigo
Idioma:Inglês
Publicado em: 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1223774/
https://ncbi.nlm.nih.gov/pubmed/12943533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20030820
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