TriKEs and BiKEs join CARs on the cancer immunotherapy highway

Por Tay, Szun Szun, Carol, Hernan, Biro, Maté
Publicado no Hum Vaccin Immunother (2016)

The anti-CD19 antibody-drug conjugate SAR3419 prevents hematolymphoid relapse post induction therapy in preclinical models of pediatric acute lymphoblastic leukemia

Por Carol, Hernan, Szymanska, Barbara, Evans, Kathryn, Boehm, Ingrid, Houghton, Peter J, Smith, Malcolm A, Lock, Richard B
Publicado em 2013

Efficacy of CPX-351, (cytarabine:daunorubicin) liposome injection, against acute lymphoblastic leukemia (ALL) xenograft models of the Pediatric Preclinical Testing Program

Por Carol, Hernan, Fan, Mannie M. Y., Harasym, Troy O., Boehm, Ingrid, Mayer, Lawrence D., Houghton, Peter, Smith, Malcolm, Lock, Richard B.
Publicado no Pediatr Blood Cancer (2014)

Pharmacokinetic Modeling of an Induction Regimen for In Vivo Combined Testing of Novel Drugs against Pediatric Acute Lymphoblastic Leukemia Xenografts

Por Szymanska, Barbara, Wilczynska-Kalak, Urszula, Kang, Min H., Liem, Natalia L. M., Carol, Hernan, Boehm, Ingrid, Groepper, Daniel, Reynolds, C. Patrick, Stewart, Clinton F., Lock, Richard B.
Publicado em 2012

Initial Testing (Stage 1) of the Kinesin Spindle Protein Inhibitor Ispinesib by the Pediatric Preclinical Testing Program

Por Carol, Hernan, Lock, Richard, Houghton, Peter J., Morton, Christopher L., Kolb, E. Anders, Gorlick, Richard, Reynolds, C. Patrick, Maris, John M., Keir, Stephen T., Billups, Catherine A., Smith, Malcolm A.
Publicado em 2009

Initial Testing (Stage 1) of the Polyamine Analog PG11047 by the Pediatric Preclinical Testing Program

Por Smith, Malcolm A., Maris, John M., Lock, Richard, Kolb, E. Anders, Gorlick, Richard, Keir, Stephen T., Carol, Hernan, Morton, Christopher L., Reynolds, C. Patrick, Kang, Min H., Houghton, Peter J.
Publicado em 2011

Initial Testing (Stage 1) the Pediatric Preclinical Testing Program of RO4929097, a γ-Secretase Inhibitor Targeting Notch Signaling

Por Kolb, E. Anders, Gorlick, Richard, Keir, Stephen T., Maris, John M., Lock, Richard, Carol, Hernan, Kurmasheva, Raushan T., Reynolds, C. Patrick, Kang, Min H., Wu, Jianrong, Houghton, Peter J., Smith, Malcolm A.
Publicado em 2011

Initial Testing of Aplidin by the Pediatric Preclinical Testing Program

Por Morton, Christopher L., Houghton, Peter J., Gorlick, Richard, Kolb, E. Anders, Lock, Richard, Carol, Hernan, Keir, Stephen T., Reynolds, C. Patrick, Kang, Min H., Maris, John M., Billups, Catherine, Smith, Malcolm A.
Publicado em 2009

Initial Testing (Stage 1) of Vorinostat (SAHA) by the Pediatric Preclinical Testing Program

Por Keshelava, Nino, Houghton, Peter J., Morton, Christopher L., Lock, Richard B., Carol, Hernan, Keir, Stephen T., Maris, John M., Reynolds, C Patrick, Gorlick, Richard, Kolb, E. Anders, Wu, Jianrong, Smith, Malcolm A.
Publicado em 2009

Initial Testing of the Aurora Kinase A Inhibitor MLN8237 by the Pediatric Preclinical Testing Program (PPTP)

Por Maris, John M., Morton, Christopher L., Gorlick, Richard, Kolb, E. Anders, Lock, Richard, Carol, Hernan, Keir, Stephen T., Reynolds, C. Patrick, Kang, Min H., Wu, Jianrong, Smith, Malcolm A., Houghton, Peter J.
Publicado em 2010

Testing of the Akt/PKB Inhibitor MK-2206 by the Pediatric Preclinical Testing Program

Por Gorlick, Richard, Maris, John M., Houghton, Peter J., Lock, Richard, Carol, Hernan, Kurmasheva, Raushan T., Kolb, E. Anders, Keir, Stephen T., Reynolds, C. Patrick, Kang, Min H., Billups, Catherine A., Smith, Malcolm A.
Publicado em 2011

Initial Testing (Stage 1) of the Multi-targeted Kinase Inhibitor Sorafenib by the Pediatric Preclinical Testing Program

Por Keir, Stephen T., Maris, John M., Lock, Richard, Kolb, E. Anders, Gorlick, Richard, Carol, Hernan, Morton, Christopher L., Reynolds, C. Patrick, Kang, Min H., Watkins, Amy, Houghton, Peter J., Smith, Malcolm A.
Publicado em 2010

Initial Testing (Stage 1) of the Polo-Like Kinase Inhibitor Volasertib (BI 6727), by the Pediatric Preclinical Testing Program

Por Gorlick, Richard, Kolb, E. Anders, Keir, Stephen T., Maris, John M., Reynolds, C. Patrick, Kang, Min H., Carol, Hernan, Lock, Richard, Billups, Catherine A., Kurmasheva, Raushan T., Houghton, Peter J., Smith, Malcolm A.
Publicado no Pediatr Blood Cancer (2013)

Initial Testing (Stage 1) of the Notch Inhibitor PF-03084014, by the Pediatric Preclinical Testing Program

Por Carol, Hernan, Maris, John M., Kang, Min H., Reynolds, C. Patrick, Kolb, E. Anders, Gorlick, Richard, Keir, Stephen T., Wu, Jianrong, Kurmasheva, Raushan T., Houghton, Peter J., Smith, Malcolm A., Lock, Richard B.
Publicado no Pediatr Blood Cancer (2014)

Initial Testing (Stage 1) of the IGF-1 Receptor Inhibitor BMS-754807 by the Pediatric Preclinical Testing Program

Por Kolb, E. Anders, Gorlick, Richard, Lock, Richard, Carol, Hernan, Morton, Christopher L., Keir, Stephen T., Reynolds, C. Patrick, Kang, Min H., Maris, John M., Billups, Catherine, Smith, Malcolm A., Houghton, Peter J.
Publicado no Pediatr Blood Cancer (2010)

Initial Testing (Stage 1) of BAL101553, a Novel Tubulin Binding Agent, by the Pediatric Preclinical Testing Program

Por Kolb, E. Anders, Gorlick, Richard, Keir, Stephen T., Maris, John M., Kang, Min H., Reynolds, C. Patrick, Lock, Richard B., Carol, Hernan, Wu, Jianrong, Kurmasheva, Raushan T., Houghton, Peter J., Smith, Malcolm A.
Publicado no Pediatr Blood Cancer (2014)

Initial Testing (Stage 1) of the Phosphatidylinositol 3’ Kinase Inhibitor, SAR245408 (XL147) by the Pediatric Preclinical Testing Program

Por Reynolds, C. Patrick, Kang, Min H., Carol, Hernan, Lock, Richard, Gorlick, Richard, Kolb, E. Anders, Kurmasheva, Raushan T., Keir, Stephen T., Maris, John M., Billups, Catherine A., Houghton, Peter J., Smith, Malcolm A.
Publicado no Pediatr Blood Cancer (2012)

Initial Testing (Stage 1) of Mapatumumab (HGS-ETR1) by the Pediatric Preclinical Testing Program

Por Smith, Malcolm A., Morton, Christopher L., Kolb, E. Anders, Gorlick, Richard, Keir, Stephen T., Carol, Hernan, Lock, Richard, Kang, Min H., Reynolds, C. Patrick, Maris, John M., Watkins, Amy E., Houghton, Peter J.
Publicado em 2010

Initial Testing of Topotecan by the Pediatric Preclinical Testing Program

Por Carol, Hernan, Houghton, Peter J., Morton, Christopher L., Kolb, E. Anders, Gorlick, Richard, Reynolds, C. Patrick, Kang, Min H., Maris, John M., Keir, Stephen T., Watkins, Amy, Smith, Malcolm A., Lock, Richard B.
Publicado em 2010

Initial Testing (Stage 1) of the Akt Inhibitor GSK690693 by the Pediatric Preclinical Testing Program

Por Carol, Hernan, Morton, Christopher L., Gorlick, Richard, Kolb, E. Anders, Keir, Stephen T., Reynolds, C. Patrick, Kang, Min H., Maris, John M., Billups, Catherine, Smith, Malcolm A., Houghton, Peter J., Lock, Richard B.
Publicado em 2010