Initial Testing (Stage 1) of Vorinostat (SAHA) by the Pediatric Preclinical Testing Program

Vorinostat, a histone deacetylase inhibitor, was evaluated against the in vitro and in vivo childhood solid tumor and leukemia models in the Pediatric Preclinical Testing Program (PPTP). In vitro testing was performed by the DIMSCAN cytotoxicity assay. In vivo, vorinostat was administered intraperit...

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Bibliografiske detaljer
Main Authors: Keshelava, Nino, Houghton, Peter J., Morton, Christopher L., Lock, Richard B., Carol, Hernan, Keir, Stephen T., Maris, John M., Reynolds, C Patrick, Gorlick, Richard, Kolb, E. Anders, Wu, Jianrong, Smith, Malcolm A.
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2752378/
https://ncbi.nlm.nih.gov/pubmed/19418547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pbc.21988
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